ABO blood groups: alleles, genotypes and antigens

Dominance and relationships of ABO alleles

More than one dominance can occur between alleles of a gene

3 alleles of ABO:

IA;IB and ii

Allele located at 9 chromosome; 3/4 are dominant and one codominant

Blood type

Type A

Type B

Type AB

Type O

Genotipo: AA o Ao

Antígenos: A

Anticuerpos: Anti-B

Genotipo: BB o Bo

Antígenos: B

Anticuerpos: Anti-A

Genotipo: AB

Antígeno: A y B

Anticuerpo: Ninguno

Genotipo: oo

Antígeno: ninguno

Anticuerpo: Anti A-B

Blood Test

Antigen reaction with antibodies

Antigen: Glycolipids(lipid + oligosaccharide)

It has 5 sugar molecules called H antigen

Modification

No-modification

Add Sugar

Type A:

A-transferasa

N-acetilglicosamina

Type B:

B-transferasa

Galactosa

Type AB:

Both

Both

Type O