Yasser is falling behind

Yasser is falling behind

1. Anatomy

2. Histology

3. Physiology

4. Slow growth rate

   • Causes
     • Endocrine
       • Genetics
         • Pregnancy environment
     • Systemic

5. Growth hormone deficiency

   • A decrease in GH. When levels are lower than 1.6 to 3.0 ng/ml for adults and 6 ng/ml for children
   • Signs and symptoms
     • Short stature
       • Chubby body build
     • Delayed tooth development
     • Delayed puberty
   • Causes
     • Congenital
       • infiltrate the hypothalamus or its connection to the pituitary gland
     • Acquired
       • tumor in the hypothalamus or pituitary
       • head trauma
       • radiation therapy
   • Pathology
     • Physical examination
       • Investigations
         • Blood tests
           • Imaging
       • Height
         • Weight
           • Body proportions
     • Management
       • GH deficiency
         • GHRH (sermorelin)
           • rGH (neutropin)
             • rIGF (mecasermine)
       • GH excess
         • Somatostatin analogs
           • GH receptor antagonists

6. Growth charts

   • Growth sprouts

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