Yasser is falling behind

Yasser is falling behind

1. Pituitary gland

   • Anatomy
   • Function
     • Posterior pituitary
       • Secretes
         • (ADH)
           • Oxytocin
     • Anterior pituitary
       • Secretes
         • ACTH
           • TSH
             • LH
               • FSH
                 • PRL
                   • GH

2. GROWTH CHARTS

   • track the growth of infants, children, and adolescents
     • Males
     • Females

3. Developmental milestones

4. maternal and child health care

   • promote
     • Therapeutic rehabilitation
       • Decrease in mortality and morbidity
   • Checkups
     • • History
       • weight
         • length
           • • Head circumference
             • Feeding
               • • Sleeping
                 • Development
                   • • physical examination

5. Hormones involved in growth

   • Growth hormone
     • Thyroid hormone
       • Insulin & IGF1
         • Androgens
     • Deficiency
       • Due to
         • 1-deficiency of anterior pituitary secretion
           • 2-Secretion of inactive growth hormone
             • 3-Hypothalamic dysfunction
               • 4-Lack of end organ response to GH
       • Leads to
         • 1-panhypopituitary dwarfism
           • 2-African Pygmy and LeviLorain dwarf
       • Treatment
         • Drugs
           • rGH:
             • sermorlin
               • mecasermin
                 • nutropin
         • Adverse effects
           • Hyperglycemia
             • Gynactomastia
               • Tumorogenesis
                 • BIH
         • Prognosis
           • catch-up growth in first year
             • waning effect

6. Hereditary causes for short stature

   • achondroplasia
     • mucopolysaccharide disease.
       • SED

7. malnutrition

   • • Stunting
     • height and weight under normal
   • • Marasmus
     • severe protein-energy deficiency
   • • Kwashiorkor
     • acute protein-energy deficiency
   • • Vitamin and mineral deficiency

8. intellectual disability

   • • Mild
     • • Moderate
       • • Severe

9. Investigations

   • Blood test
     • (DXA) scan
       • MRI
         • X-ray

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