Cystic Fibrosis

Cystic Fibrosis

1. Genetic Disorder

   • Autosomal Recessive
   • Abnormal Exocrine Gland Function
   • Excessive Salt in Sweat
   • Most common Lethal Disease in Whites
   • Median Lifespan 25 years

2. Diagnosis

   • Prenatal
     • Chromosome Testing
   • Postnatal
     • Sweat Chloride Test

3. Pancreatic Involvement

   • Lack of Trypsin - malabsorption
   • Rectal Prolapse
   • Meconium Ileus
   • Liver Cirrhosis
   • Gallstones
   • Salivary Gland Obstruction

4. Pulmonary Involvement

   • Excessive Mucus
   • Reduced Cilia Function
   • Recurrent Infections