Important receptor sites within the body

Important receptor sites within the body

1. Beta

   • Beta 2
     • Agonist Effect
       • Lungs
         • Bronchus and Bronchiole relaxation
       • Arterial
         • Arterial dilation in certain key organs
       • Pancreas
         • insulin secretion
       • Renal
         • Uterine relaxation
   • Beta 1
     • Heart
       • Increased heart rate (chronotropy effect)
       • Increased myocardial contractility (inotropic effect)
       • Increased myocardial conduction (dromotropic effect)
     • Renal
       • Renin secreation for urinary retention

2. Alpha

   • Alpha 1
     • Arteries and veins
       • Vasoconstriction
   • Alpha 2
     • Pancreas
       • Insulin retention
       • Glucagon Secretion
     • adrenal medulla
       • inhibition of norepinephrine release

3. Dopaminergic

   • Vasodilation of renal and mesenteric arteries

4. Nicotinic

   • Present at neuromuscular junction, allowing ACh to stimulate muscle contraction

5. Muscarinic-2

   • Heart
     • Activated by ACh to offset stimulation of the sympathetic nervous system
       • Decreasing
         • Heart rate
         • contractility
         • Electrical conduction velocity

6. Opioid

   • PNS and CNS, bowels, and various tissues
     • analgesia
     • euphoria
     • respiratory depression