Beta Receptors

Beta Receptors

1. B1

   • Heart
     • Increase
       • Heart rate
         • + Chronotropic
       • Impulse conduction
         • + Dromotropy
       • Contraction
         • + Intropy
       • Ejection fraction
     • Beta Blocker
       • Decrease
         • Contractility
           • – Intropy
         • Conduction velocity
           • – Dromotropy
         • Relaxation rate
           • – Lusitropy
         • Heart rate
           • – Chronotropic
   • Kidney
     • Increase
       • Renin release by Juxtaglomerular cells
         • Beta Blocker
           • Decrease
             • Renin release by Juxtaglomerular cells
   • Gastrointestinal tract
     • Increase
       • Hunger
         • ↑ Ghrelin release by stomach
           • Beta Blocker
             • ↓ Ghrelin release by stomach
               • Decrease
                 • Hunger

2. B2

   • Smooth muscle
     • Relaxation
       • Bronchus
       • Bronchioles
       • Detrusor muscle
       • Uterine muscle
       • Beta Blocker
         • (Mild) Constriction
           • Bronchus
           • Detrusor muscle
           • Bronchioles
           • Uterine muscle
   • Contraction of urethral spinchter
     • Beta Blocker
       • Relaxation
   • Kidney
     • Increase
       • Renin release by Juxtaglomerular cells
         • Beta Blocker
           • Decrease
             • Renin release by Juxtaglomerular cells
   • Glucose metabolism
     • Inhibits
       • Insulin release
     • Stimulate
       • Gluconeogenesis
       • Glucolysis
     • Beta Blocker
       • Stimulate
         • Insulin release
       • Inhibits
         • Gluconeogenesis
         • Glucolysis
   • Lypolysis
     • Beta Blocker
   • Thickened salivary secretion
     • Beta Blocker