Leishmaniasis

Leishmaniasis

1. SKIN

   • Physiology of the skin
     • It consists of the skin & its accessories (hair, nails, cutaneous glands).
     • Functional structures of the skin
       • Sensation millions of nerve endings
       • Heat regulation Sweating/ BloodFlow/ thermoreceptors
       • Absorption vitamins, acids, water and oxygen
       • Protection Toxics/radiation /pollutants
       • Excretion Toxics/sweat/ ammonia
       • Secretion Sebum/acid mantle.
       • Facial Expressions
   • Histology of the skin

2. Types

   • Cutaneous
     • Localized
     • Diffuse
     • Leishmania recidivans
       • Exaggerated hypersensitivity reaction
     • Post Kala Azar Dermal Leishmaniasis
     • Cutaneous leishmaniasis lesions may be papular, nodular and ulcerative
     • Cause by Leishmania tropica
   • Muco- cutaneous
   • Visceral
   • Viscerotropic

3. Life cycle and transmission

4. Pathogenesis

5. Signs and symptoms

   • Breathing difficulty
   • Skin sores
   • Stuffy nose, runny nose, and nosebleeds
   • Swallowing difficulty
   • Ulcers
   • Fever
   • Weight loss
   • Abdominal discomfort

6. Risk factors

7. Investigations

8. Treatment

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