Breast Lump

Breast Lump

1. Breast Anatomy

2. Breast Cancer

   • Types
     • Benign
       • Most changes are caused by combination of cysts and fibrosis
         • Causes breast swelling and pain
     • Malignant
       • Ductal Carcinoma
       • Lobular Carcinoma
       • Inflammatory Breast Cancer
   • Genetic types and Modes of Inheritance
     • BRCA 1 & 2 Mutations
       • DNA repair genes
     • p53 Mutations
       • Tumor suppresser gene
   • isk Factors
     • Female gender - Age - Family History Personal history of breast cancer Radiation to chest before the age of 30 - Race/ Ethnicity - Overweight and fatty food - Pregnancy(above 30 years) Breast Feeding history Hormonal Replacement therapy Drinking alcohol
   • Management
     • Stage I and II
       • Modified radical mastectomy Breast-conserving therapy (BCT), chest wall radiation, and systemic adjuvant therapy
     • Stage III
       • Chemotherapy and adjunvent radiotherapy
     • Stage IV
       • Supportive care
   • Breast Examination and Screening
     • Screening mammography Diagnostic mammography

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