Zusammenfassung der Ressource
Examples of Proteins
- Conjugated Proteins
- ions and non-protein molecules
attached to them
- when the attachment is a
requirement it is called a
prosthetic group.
- active complex = holoenzyme and
protein alone = apoenzyme.
- carbohydrate attachments
- amino acids serine or threonine
or asparagine
- Extracellular matrix proteins
- elongated and fibrous
- dense connective tissue is made of collagen.
- Collagen
- first made as procollagen = three helices
wound round each other
- after assembly procollagen is cleaved
together to form tropocollagen
- tropocollagen = left handed helix
- proline and lysines are hydroxylated after
synthesis. This requires vit C and failure results
in scurvy.
- stabilising = formation of cross links between
lysines at the end of tropocollagen