Zusammenfassung der Ressource
The malfunction of a CELL, NOT A MOLECULE, is the fundamental driver of disease
- Malfunction of a CELL
- Organelles
- Mitochondria
- functions of organelles
- Disease associated with organelle malfunction
- Cell trafficking
- protein misfolding
- Enviromental factors
- Oxidative Stress
- Genetical malfunctions
- Cell signalling
- Malfunction of a MOLECULE
- Definition
- a molecule is group of atoms covalently bonded togehter
- macromolecules
- protein/lipids/carbohydrates
- DISEASES due to SINGLE MUTATION
- SILENT MUTATIONS
- change in molecule but no change in cell
- INTERPLAY of BOTH
- Changes in the molecular level start a chain reaction which eventually leads cell malfunction
- a single molecule rarely causes disease: its the combined effect of different factors