Zusammenfassung der Ressource
Hypertension
- Epidemiology
- Increase peripheral
resistance
- Arteriolar
Vasoconstriction
- Increase Blood
Volume
- Most common
diagnosis in the US
- Primary
- Genetics
- Environmental
- Neruohumoral
- SNS
- RAAS
- Natriuretic
Peptides
- Inflammation
- Secondary
- Result of
another disease
- Renal
- Parenchymal
- Tumors
- Adrenocortical
- Adrenomedullary
- Medications
- Oral
contraceptives
- Corticosteroids
- Antihistamines
- Complicated
- Chronic
- Pathophysiology
- Urologic
System
- Increases RAAS
- Increases Angiotensin II
- Endothelial Dysfunction
- Na
retention
- H2O
retention
- Hyperuricemia
- Glomerular remodeling
- Nephrosclerosis
- Autonomic dysregulation
- Nervous
System
- Vascular
remodeling
- Inflammation
- Oxidative
Stress
- Baroreflex
dysfunction
- Atherosclerotic
plaque
- Liphyalinosis
- Vascular Stiffening
- STROKE
- Risk
Factors
- ≥ 60
years
old
- Blacks
- Diabetic
- Family
History
- Smoking
- Obesity
- Heavy
ETOH
- High: Na
low: K,
Ca, Mg
- Clinical
Presentation
- Asymptomatic
- Complications to
damaged organs
- Heart disease
- Renal insufficiency
- CNS dysfunction
- Impaired vision
- Impaired mobility
- Vascular occlusion
- Edema
- Diagnose
- SBP ≥ 140mg Hg
DBP ≥90mm Hg
- Elevated
pressures
x2
- CBC
- ECG
- History
- Physical
- 24-hr BP
monitor
- Biochemical blood
profile
- Treat
- Lifestyle modifications
- Weight loss
- Exercise
- Smoking cessation
- Dietary
modifications
- Medication
- Diuretics
- ACE inhibitor
- ARB
- Ca channel blocker
- Aldosterone antagonist
- Beta-blockers
- Monitor