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PSIO 404 Exam I

Nhan Tran 14 Fragen Aktualisiert am 18 Jan 2017

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  1. 1Which of the following is a covalent post-translational modification of signal proteins which is also ATP-independent?
    1. APhosphorylation
    2. BGTP Hydrolysis
    3. CNitrosylation
    4. DOxidation
  2. 2Which of the reactive oxygen species (ROS) is the most dangerous to cells?
    1. AHydrogen peroxide (H2O2)
    2. BSuperoxide anion radical (O2*-)
    3. CHydroxyl radical (OH*)
  3. 3When a signaling protein hydrolyzes a nucleotide triphosphate, order is produced. The resulting order is reflected in the formation of more protein-protein interactions.
    1. ARichtig
    2. BFalsch
  4. 4For a generic switching reaction, which of the following statements is the most correct?
    1. ASwitching a signal-processing protein "ON" always requires energy.
    2. BSwitching a signal-processing protein "ON" or "OFF" requires energy, but only one direction for the switch must be linked to an energy-supplying reaction.
    3. CSwitching a signal-processing protein "OFF" always requires energy.
    4. DSwitching a signal-processing protein "ON" always requires energy, and switching a signal-processing protein "OFF" also always requires energy.
  5. 5Which of the following terms refers to the way in which the binding of signal molecules alter conformation equilibrium for signal-processing proteins?
    1. Aallostery
    2. Bscaffolding
    3. Ccovalent interaction
    4. Dadaptation
  6. 6Which of the following is not a strategy for maintaining and improving stability in a signal-processing system?
    1. Anoise filtering
    2. Bredundancy
    3. Cencoding
    4. Dpattern generation
    5. Eadaptation
  7. 7Which of the following types of proteins acts to vastly speed up signal transduction by pre-assembling signaling proteins into a signaling complex?
    1. Anoise-filtering proteins
    2. Bproteins with one or more isoforms (alternatively-spliced proteins)
    3. Cadaptor proteins
    4. Dscaffold (scaffolding) proteins
  8. 8Which statement is false?
    1. AThe data-processing protein network ("brain") of a cell takes advantage of the modular design of proteins to link specific outputs to specific inputs.
    2. BThe data-processing protein network ("brain") of a cell employs at least 4 mechanisms to maintain and improve stability.
    3. CThe data-processing protein network ("brain") of a cell controls the availability and non-availability of interaction domains to govern how a signal is processed
    4. DThe data-processing protein network ("brain") of a cell uses proteins as switching elements.
    5. EThe data-processing protein network ("brain") of a cell rarely links short-range and long-range signaling during signal transduction.
  9. 9Which family of proteins acts as unfoldases to dissociate protein-protein and protein-nucleic acid complexes?
    1. Athe large (trimeric) G-protein family
    2. Bthe small G-protein family
    3. Cthe chaperone family
    4. Dthe AAA+ protein family
  10. 10Chaperone proteins such as heat shock protein 90 (Hsp90) use the energy of _____ hydrolysis to enable misfolded steroid hormone receptors to go from native state (stable but non-functional state) to functional state.
    1. AATP
    2. Bglutathione
    3. Cphosphoenol pyruvate (PEP)
    4. DGTP

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Erstellt am 29 Jan 2016 · aktualisiert am 18 Jan 2017
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