Immunology 1

1

What is the best description of an infectious agent?

1

Advantages of infecting a host to a pathogen are:

P
provision
Travel

Disadvantages are:

Host driven
mechanisms encountered

1

True or false?

1

The response of the innate immune system is the same every time

1

The first encounter of the adaptive immune system is very rapid.

1

The innate immune system has a memory property.

1

What are some physical barriers of the innate immune system?

1

Which of these options summarises lysozymes action?

1

Which of these options summarises lactoperoxidase's action?

1

Which of these options summarises lactoferrin's action?

1

Which of these options summarises calprotectin's action?

1

Which of these options summarises defensin action?

1

Which of these options summarises histatin action?

1

Which is a function of mucins?

1

Which is a function of salivary agglutinin?

1

Defensins are...

1

What feature of defensins allows them to become inserted in the lipid bilayer?

1

Defensins, cathelicidins and histatins are antimicrobial peptides all secreted by...

1

What does NAG mean in the context of lysozyme?

1

What does NAM mean in the context of lysozyme?

1

What linkage is cleaved between NAG-NAM carbohydrates by Lysozyme?

1

Lysozyme is more effective against gram negative bacteria since they do not have a layer of LPS covering the peptidoglycan NAG-NAM carbohydrates in their cell wall structure

1

Histatins are produced by

1

Histatins are predominantly active against

1

Histatins are particularly rich in...

1

Calprotectin depletes iron availability.

1

Lactoferrin produces hypothiocyanite which oxidises glucose transport carriers therefore reducing bacterial glucose uptake

1

Chromogranin A and Thrombospondin 1 give rise to cationic peptides. They interact better with plant/animal cells than bacterial surfaces.

1

Cystatins are

1

What is gingipains?

1

SLP1 is a

1

Cystatins and Von Ebner's protein are both cysteine protease inhibitors

1

Cystatins, Von Ebners protein and SLP1 are all cysteine protease inhibitors

1

Which scavenges peroxidation products?

1

Toll like receptors react to...

1

NOD-like receptors detect intracellular virus RNA

1

NOD-like receptors detect intracellular pathogen peptidoglycan

1

NOD-like receptors detect intracellular pathogen p

1

RIG-1 like helicase detect intracellular R

1

NLRP family of proteins are nod like receptors with pyrin associated with them

1

The inflammasome is important in cleaving cytokines and contributes to their short half life

1

NLRP3 is the only NLRP protein to form inflammasomes

1

What are the components of the typical inflammasome?

1

Activation of toll like or nod like receptors results in what?

1

Which of these are serum proteins?

1

Which of these are tissue factors?

1

Acute phase proteins are produced by the

1

C reactive protein is a protein made by h

1

C reactive protein activates...

1

.

Immunology 1

What is the best description of an infectious agent?

Advantages of infecting a host to a pathogen are: P provision Travel Disadvantages are: Host driven mechanisms encountered

True or false?

The response of the innate immune system is the same every time

The first encounter of the adaptive immune system is very rapid.

The innate immune system has a memory property.

What are some physical barriers of the innate immune system?

Which of these options summarises lysozymes action?

Which of these options summarises lactoperoxidase's action?

Which of these options summarises lactoferrin's action?

Which of these options summarises calprotectin's action?

Which of these options summarises defensin action?

Which of these options summarises histatin action?

Which is a function of mucins?

Which is a function of salivary agglutinin?

Defensins are...

What feature of defensins allows them to become inserted in the lipid bilayer?

Defensins, cathelicidins and histatins are antimicrobial peptides all secreted by...

What does NAG mean in the context of lysozyme?

What does NAM mean in the context of lysozyme?

Advantages of infecting a host to a pathogen are:

P
provision
Travel

Disadvantages are:

Host driven
mechanisms encountered