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Regarding the transcellular fluid ?
Its volume can reach up to 5% of TBW in some normal humans
Its volume is affected by dehydration and overhydration .
t is a specialized type of ICF
it is the same as interstitial fluid
Its compositions differs markedly from that of plasma and interstitial fluid .
A normal subject with 37.5 C body temperature , exposed to overheating , his temperature is increased to 37.8 C , if his thermostatic control is impair his body temperature is increase to 43.5 , what is the gain of his control system ?
-6
-7.5
-40
-19
-30
Hyperglycemia(too much glucose in blood) causes insulin release , formation of glycogen by the liver and glucose urea , this combination represent :
The gain of the feedback mechanism
Negative feedback mechanism
Positive feedback mechanism
Integrated response
Disturbance of feedback control
Treatment of the disease can be done by all of the following EXCEPT
Potentiating(strengthening) of the positive feedback mechanism
Blocking the positive feedback mechanism
Helping the negative feedback mechanism
Helping the organ to increase its function
Blocking the stimulus of the feedback mechanism
The osmolarity of a solution formed of 1L of water containing ; 1 mol of each glucose , NaOH , Al(OH)3 :
30 mOsm/L
1 mOsm/L
3 mOsm/L
4 mOsm/L
7 mOsm/L
Which of the following mechanism is not rate limited by Vmax
Transport of glucose across the cell membran
Transport of CO2 across the cell membrane
Transport of Na ion through Na-K pump
Co-transport of Cl ion through Na-Cl channel
Counter transport of H+ and K+ by H+ pump
Diffusion of blood gasses across the cell membrane is affected by all the following EXCEPT
The osmotic pressure
The partial pressure of the specific gas
The concentration gradient
The temperature
The kinetic energy
Which one of the following has the highest (mOsm) in 1 L of plasma
2 millimole of fructose
1 millimole of KCl
5 millimole of glucose
2 millimole of CaCl2
2 millimole of albumin
Which of the following solutions when infused intravenously would result in an increase in extracellular fluid volume, a decrease in intracellular fluid volume, and an increase in total body water after osmotic equilibrium? (isotonic % of solutes in cells is 0.9%)
1 L of 0.9% sodium chloride solution
1 L of 0.45% sodium chloride solution
1 L of 3% sodium chloride solution
1 L of 5% fructose solution
1 L of pure water
An increase in which of the following would be expected to decrease blood flow in a vessel
Pressure gradient across the vessel
Radius of the vessel
Plasma colloid osmotic pressure
Viscosity of the blood
Plasma sodium concentration
Which blood vessel has the highest vascular resistance
Blood flow (ml/min) pressure gradient (mm Hg)
1000 100
Blood flow (ml/min) pressure gradient (mm Hg) 1200 60
Blood flow (ml/min) pressure gradient (mm Hg) 1400 20
Blood flow (ml/min) pressure gradient (mm Hg) 1600 80
Blood flow (ml/min) pressure gradient (mm Hg) 1800 40
Nernst equation
Calculates the diffusion potential .
Calculates the membrane potential under the effect of more than one ion
Calculates the equilibrium potential for one ion at a time
Calculates the equilibrium potential of K ion to be about 61 mV
Calculates the equilibrium potential of Na ion to be about - 94 mV
A person with normal body fluid volumes weighs 60 kg and has an extracellular fluid volume of approximately 12.8 L, a blood volume of 4.3 L, and a hematocrit of 0.4; 57% of his body weight is water.
What is the approximate interstitial fluid volume?
6.4 L
8.4 L
10.2 L
11.3 L
12.0 L
The diameter of a precapillary arteriole is increased in a muscle vascular bed. A decrease in which of the following would be expected
Capillary filtration rate
Vascular conductance
Capillary blood flow
Capillary hydrostatic pressure
Arteriolar resistance
A man with lean body mass of 65 kg was injected with 10ml of water with 1% of it being labelled liquid with the same density as water. After that blood plasma was sampled and found to contain 0.037 mg/ml of labelled liquid. What is the volume of plasma?
2.70 litres
0.27 litres
27 litres
5 litres
After we have measured the extracellular fluid volume of this man.What is the most suitable way to measure volume of intracellular fluid?
Use sodium as a label to find volume by law of mass conservation
Use potassium ions as a label to find volume by law of mass conservation
Use labelled water as a label to find volume by law of mass conservation
There is no need for labels.Volume of extracellular fluid can be found by subtracting extracellular volume from total body water volume
Which of the following is the most serious consequence of Hyponatremia-dehydration?
diarrhea
sweating
breathing problems
intracellular edema in cerebellar cells(herniation),which causes very painful pressure on nerves
What is the most serious consequence of hypernatremia?
tear in blood vessels and hemorrhage
skin turgor
weight loss
tachycardia
Edema can be caused by all of these factors except
an increase in the plasma protein concentration
obstruction of lymphatic vessels
increased capillary permeability because of inflammation
increased venous pressure
The resting membrane potential
occurs only in nerve and muscle cells
Is the same in all cells
is oriented so that the cell’s interior is positive with respect to the extracellular fluid
requires the movement and diffusion of all ions of cells
none of the above
Which of the following statements about the rate at which action potential travels in neurons is true?
The direction of its travel is unidirectional(spreads to one direction only)
It is faster for a strong stimulus than a weak one
It is faster for myelinated fibres than in non-myelinated ones
a and c
a,b,and c
Which of the following will not decrease of we cut a limp
Cardiac output
total vascular conductance
Resistance of each blood vessel
all of the above
Which of the following is/are true about turbulence?
It is less likely to occur at low flow than at a high flow
Turbulence would more likely occur at a large vessel than in a small vessel
For a fixed flow,turbulence is most likely to occur in a high viscosity fluid than in a low viscosity fluid
Turbulence is noisier than laminar flow
a and d
The main factor responsible for the high viscosity of blood is the small non-cellular proteins dissolved in the plasma
Which statement about action potential is false
only a relatively small number of Na+ and K+ions actually diffuse across the membrane
The production and spread of action potential is an example of both positive feedback and negative feedback
During the production of action potential.Na+ and K+ total concentration( both intracellular concentration and extracellular concentration of one ion added together)does not change
Na+/K+ pumps are directly involved in creating the action potential
If resistance in a blood vessel has doubled, but flow has change,then the pressure difference at the ends of the tube must be the double also
How can a cell be compared to solution containing 400 mOSM of urea only
urea is iso-osmotic but hypertonic
urea is hyperosmotic but hypotonic
urea is hyperosmotic and hypertonic
Urea is hypo-osmotic and hypotonic
Which of the following affects proportions of body fluids to each other
%of body fat
Size of the body
Sleeping
Change in solute concentration inside cells
The membrane potential will depolarize by the greatest amount if the membrane permeability increases for
Potassium
Sodium and potassium
Chloride
Potassium and chloride
Sodium
A cell present on a dish in a lab has an osmolarity of 300osm/l.while a soltion on another table has an osmolarity of 200 osm/l.The cell (in comparision to solution)is
hyperosmolar
hypo-osmolar
hypertonic
hypotonic