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Chondrocyte Proliferation can be inhibited through activation of the ( D, C, B, A ). ( A, B, C, D ), secreted locally by chondrocytes and by the liver, stimulates chondrocyte proliferation. This same chemical also promotes Cartilage Matrix Secretion along with ( C, B, A, D ).
Chondrocyte Hypertrophy is inhibited by local production and binding of ( B, A, C, D )
Options:
A = IGF-1
B = Parathyroid Hormone related Peptide
C = BMPs
D = Fibroblast Growth Factor 3 Receptor