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281 - Pacemaker action potential (add)

Gelöschter Nutzer Der Nutzer hat seine Fachbereichs-Information gelöscht. Englisch 10 Karten

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  1. 1Pacemaker action potential occurs in what nodes?SA and AV nodes.
  2. 2Describe Phase 0upstroke—opening of voltage-gated Ca2+ channels. Fast voltage-gated Na+ channels are permanently inactivated because of the less negative resting potential of these cells. Results in a slow
    conduction velocity that is used by the AV node to prolong transmission from the atria to ventricles.
  3. 3Describe Phase 1Phase 1 is absent
  4. 4Describe Phase 2Phase 2 is absent
  5. 5Describe Phase 3inactivation of the Ca2+ channels and increased activation of K+ channels ---> increased K+ efflux.
  6. 6Describe Phase 4slow spontaneous diastolic depolarization due to If (“funny current”). If channels responsible for a slow, mixed Na+/K+ inward current; different from INa in phase 0 of ventricular action potential. Accounts for automaticity of SA and AV nodes. The slope of phase 4 in the SA node determines HR. ACh/adenosine decreases the rate of diastolic depolarization and decreases HR, while
    catecholamines increases depolarization and increases HR. Sympathetic stimulation increases the chance that If channelsare open and thus increases HR.
  7. 7In Phase 4, slow spontaneous ___________ ____________ due to If (“funny current”)Slow spontaneous diastolic depolarization due to If (“funny current”)
  8. 8In Phase 4, ___________ decreases the rate of diastolic depolarization and decreases HR, while ___________ increases depolarization and increases HR.ACh/adenosine decreases the rate of diastolic depolarization and decreases HR, while catecholamines increases depolarization and increases HR.
  9. 9In Phase 4, The________ of phase 4 in the SA node determines _________The slope of phase 4 in the SA node determines HR
  10. 10In Phase 4, Sympathetic stimulation increases the chance that If channels are open and thus _________ _________Sympathetic stimulation increases the chance that If channels are open and thus increases HR.

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Beschreibung
Der Nutzer hat seine Fachbereichs-Information gelöscht. Karteikarten am 281 - Pacemaker action potential (add), erstellt von Gelöschter Nutzer am 30/05/2017.
Erstellt von
Gelöschter Nutzer · Mai 2017
Aktualisiert
30 Mai 2017
Aufrufe
21
Verlauf
  • Erstellt von Victoria Wright · 30 Mai 2017
  • Kopiert von Victoria Wright · 30 Mai 2017
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