Lupus CS

Question 1

Ce NU este caracteristic lupusului eritematos sistemic?

Accepted Answer

Endocardita eozinofilică

Answer

Pneumonita

Answer

Pericardita

Answer

Endocardita Libmann-Sacks

Answer

Miocardita

Question 2

Ce modificare hematologică NU este caracteristică lupusului eritematos sistemic?

Accepted Answer

Leucocitoza

Answer

Leucopenia

Answer

Anemia hemolitica

Answer

Trombocitopenia

Answer

VSH crescut

Question 3

Care valve cardiace se afectează mai frecvent în lupusul eritematos sistemic?

Accepted Answer

Mitrale

Answer

Aortice

Answer

Tricuspide

Answer

Pulmonare

Answer

Mitrale si tricuspide

Question 4

Ce este mai caracteristic pentru lupusul eritematos sistemic?

Accepted Answer

Insuficienţa mitrală

Answer

Stenozamitrală

Answer

Insuficienţa aortică

Answer

Stenoza aortică

Answer

Insuficienţa tricuspidă

Question 5

Semnul urinar al glomerulonefritei lupice, conform criteriilor diagnostice, este:

Accepted Answer

Proteinuria

Answer

Hematuria

Answer

Leucocituria

Answer

Uraturia

Answer

Bacteriuria

Question 6

Ce variantă de nefrită lupică are cel mai sever prognostic?

Accepted Answer

Nefropatia lupică difuză sclerotică (>90% glomeruli sclerozaţi)

Answer

Nefropatia lupică mezangială minimă

Answer

Nefrita lupică mezangială proliferativă

Answer

Nefropatial upică focală sclerotică inactivă

Answer

Nefropatia lupică membranoasă (proteinurie 3g/zi)

Question 7

Celulele lupice reprezintă:

Accepted Answer

Polinucleare mature ce au fagocitat nucleele leucocitelor degradate

Answer

Macrofage, ce au fagocitat nucleele leucocitelor degradate

Answer

Aglomerări de limfocite

Answer

Aglomerări de nuclee ale leucocitelor degradate

Answer

Celule spumoase degradate

Question 8

Ce afirmaţie este caracteristică lupusului eritematos?

Accepted Answer

Titrul anticorpilor ANA creşte

Answer

IgG serică scade

Answer

Complexe imune circulante în limite normale

Answer

IgM serică scade

Answer

Prezenta anticorpilor anti-CCP

Question 9

Diagnosticul pozitiv de lupus eritematos sistemic necesită cel puţin câte criterii ACR (1997)?

Accepted Answer

4 criterii

Answer

3 criterii

Answer

6 criterii

Answer

8 criterii

Answer

11 criterii

Question 10

Indicaţi doza de corticosteroizi unui bolnav cu nefropatie lupică severă:

Accepted Answer

1,0-2,0 mg/kg/zi

Answer

0,1-0,5 mg/kg/zi

Answer

0,75 mg/kg/zi

Answer

3,0-4,0 g/kg/zi

Answer

>4 g/kg/zi

Question 11

Care fenomen este caracteristic lupusului eritematos sistemic?

Accepted Answer

Activarea limfocitelor T-helper

Answer

Activarea limfocitelor T-supresor

Answer

Inhibarea limficitelor B

Answer

Inhibarea limfocitelor T-kiler

Answer

Activarea limfocitelor T-citotoxice

Question 12

Durata tratamentului cu corticosteroizi în lupusul eritematos sistemic este:

Accepted Answer

Toata viata

Answer

1 luna

Answer

3-6 luni

Answer

1 an

Answer

2 ani

Question 13

Manifestarea cardiacă cea mai frecventă în lupusul eritematos sistemic este:

Accepted Answer

Pericardita

Answer

Miocardita

Answer

Endocardita lupică

Answer

Valvulopatiile

Answer

Aritmiile cardiace

Question 14

Medicamentul cel mai puţin toxic în lupusul eritematos sistemic este:

Accepted Answer

Hidroxiclorochina

Answer

Clorambucilul

Answer

Ciclofosfamida

Answer

Azatioprina

Answer

Metotrexatul

Question 15

Cel mai eficace medicament în tratamentul nefritei lupic este:

Accepted Answer

Ciclofosfamida

Answer

Metotrexatul

Answer

Azatioprina

Answer

AINS

Answer

Corticosteroizii

Question 16

Riscul de a dezvolta nefropatie lupică au pacienţii cu:

Accepted Answer

Titrul crescut de anticorpi anti ADNdc

Answer

Anomalii urinare periodice

Answer

Hipercomplementemie

Answer

VSH foarte crescut

Answer

Trombocitopenie

Question 17

Cea mai frecventă manifestare a lupusului cardiac este:

Accepted Answer

Pericardita

Answer

Miocardita

Answer

Afectarea tuturor valvelor

Answer

Endocardita Libman-Sacks

Answer

Infarctul de miocard

Question 18

Cea mai frecventă manifestare a afectării sistemului nervos în lupusul eritematos sistemic este:

Accepted Answer

Depresia

Answer

Anxietatea

Answer

Cefaleea

Answer

Disfuncţia cognitivă uşoară

Answer

Psihoza

Question 19

Care dintre următorii anticorpi au incidenţa cea mai mare în lupusul eritematos sistemic:

Accepted Answer

Anti-ADN dc

Answer

Anti-centromer

Answer

Anti-J01

Answer

Anti-streptolizina O sau S

Answer

Anti-hialuronidaza

Question 20

Manifestarea cutanată cea mai caracteristică pentru lupus eritematos sistemic este:

Accepted Answer

Rash malar în formă de fluture

Answer

Eritem discoid

Answer

Alopecie

Answer

Livedo reticularis

Answer

Fenomen Raynaud

Lupus CS

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