GoConqr hat ein neues Design! Sag uns, wie es dir gefällt.

Kostenlos registrieren

Quiz

Routes of Administration

Crystal Yu 17 Fragen Aktualisiert am 22 Mär 2018

Quiz starten

Dieses Quiz enthält Fragetypen, die sich im gewohnten Player öffnen.

Fragen in diesem Quiz (17)

  1. 1Limiting factors that restrict drugs to certain dosage forms:
    • [blank_start]Solubility[blank_end]
    • [blank_start]Stability[blank_end]
    • [blank_start]Absorption[blank_end]
    • [blank_start]First pass[blank_end] effect
    • [blank_start]Dose[blank_end]
    1. ASolubility
    2. BStability
    3. CAbsorption
    4. DFirst pass
    5. EDose
  2. 2[blank_start]Sublingual[blank_end], [blank_start]buccal[blank_end], and [blank_start]IV[blank_end] dosage forms have a quick effect and reach maximum plasma concentration a lot faster after administration.
    1. ASublingual
    2. Bbuccal
    3. CIV
  3. 3[blank_start]Oral[blank_end] and [blank_start]ointment[blank_end] dosage forms reach its maximum plasma concentration a long time after administration.
    1. AOral
    2. Bointment
  4. 4Sublingual route dosage forms:
    - Tablets
    - [blank_start]Troches[blank_end]
    - [blank_start]Lozenges[blank_end]
    1. ATroches
    2. BLozenges
  5. 5Disadvantages of the oral route:
    - [blank_start]First pass[blank_end] effect
    - Unpredictable absorption due to factors such as [blank_start]diet[blank_end] and [blank_start]age[blank_end] that affect bioavailability
    1. AFirst pass
    2. Bdiet
    3. Cage
  6. 6If a drug is administered in a soluble form or it dissolves rapidly, [blank_start]membrane transport[blank_end] will become rate limiting step
    1. Amembrane transport
  7. 7Dissolution rate from highest to lowest are as following:
    [blank_start]Liquids[blank_end] and [blank_start]solutions[blank_end] > [blank_start]Suspensions[blank_end] > [blank_start]Capsules[blank_end] > [blank_start]Tablets[blank_end]
    1. ALiquids
    2. Bsolutions
    3. CSuspensions
    4. DCapsules
    5. ETablets
  8. 8[blank_start]Intrinsic dissolution[blank_end]: Dissolution rate that is specific to each drug
    - This is characterized by Noyes-Whitney equation
    1. AIntrinsic dissolution
  9. 9Factors affecting intrinsic dissolution:
    Increase in [blank_start]temperature[blank_end] = Increase in rate of dissolution (affects Cs)
    Decrease in [blank_start]viscosity[blank_end] = Increase in rate of dissolution (affects D)
    [blank_start]Agitation[blank_end] (mixing/taking with food) = Increase in rate of dissolution (affects h)
    Change in [blank_start]pH[blank_end] = Affects Cs
    Decrease in [blank_start]size[blank_end] = Increase in rate of dissolution (affects S)
    1. Atemperature
    2. Bviscosity
    3. CAgitation
    4. DpH
    5. Esize
  10. 10Factors affecting solubility:
    - [blank_start]Polymorphism[blank_end] (diamonds vs graphite)
    - [blank_start]Hydrated[blank_end] vs [blank_start]anhydrous[blank_end] form (thirsty)
    - [blank_start]Salt[blank_end] form (depends on drug)
    1. APolymorphism
    2. BHydrated
    3. Canhydrous
    4. DSalt

Informationen

Beschreibung
- Why do we need different routes of administration? - What are the most common route of administration? - What are the biopharmaceutical characteristics in terms of Absorption, Distribution, Metabolism and Elimination (ADME) dictating the fate of drugs from each routes of administration
Sprache
English
Aufrufe
52
Verlauf
Erstellt am 21 Mär 2018 · aktualisiert am 22 Mär 2018
Bewertung
Noch keine Bewertungen
Bewerte dieses Quiz
Bewerte dieses Quiz

Feedback

Worum geht es?

Wie gefällt dir das neue Design?

Dein Eindruck