Quiz
31-60 Pathophys sem 6
Erstelle ein kostenloses Konto, um dieses Quiz zu beenden
Speichere deinen Fortschritt und sieh dir dein Endergebnis an.
oder mit deiner E-Mail registrieren
Schon ein Konto? Anmelden
Fragen in diesem Quiz (44)
130. What are the etiologic factors of folate deficiency anemia?
- Aa) Erythrocytes are: macrocytes, hyperchromic and of various shapes and sizes
- Bb) Erythrocytes are: microcytic, hyperchromic and of various shapes and sizes
- Cc) Erythrocytes are: macrocytes, hypochromic and of various shapes and sizes
- Dd) Erythrocytes are: microcytic, hyperchromic and of the same shape
and size - Ee) Erythrocytes are: microcytic, hypochromic and of the same shape and size
231. What is the pathogenetic mechanism of iron deficiency anemia in chronic inflammation?
- AIncreased level of hepcidin which inhibits ferroportin and Fe2+ release from enterocyte
- BReduced level of hepcidin which inhibits ferroportin and Fe2+ release from enterocyte
- CIncreased level of hephaestin which inhibits ferroportin and Fe2+ release from enterocyte
- DReduced level of hephaestin which inhibits ferroportin and Fe2+ release from enterocyte
- EReduced level of hemopexin which inhibits ferroportin and Fe2+ release from enterocyte
331. What is the pathogenetic mechanism of iron deficiency anemia in chronic inflammation?
- AIncreased hephaestin level
- BIncreased haptoglobin level
- CIncreased hepcidin level
- DIncreased hemopexin level
- EIncreased ferroportin level
432. What is the pathogenetic mechanism of iron deficiency anemia in chronic inflammation?
- AA) Autoimmune destruction of erythroid precursor cells in the bone marrow
- BB) Chronic blood loss from the gastrointestinal tract due to inflammation
- CC) Hepcidin-mediated sequestration of iron within macrophages, blocking its release for erythropoiesis
- DD) Vitamin B12 deficiency caused by gastric mucosal atrophy
- EE) Increased destruction of red blood cells by a hyperactive spleen
533. What are the pathogenetic factors involved in the development of iron deficiency anemia?
- Aa. Megalocytosis.
- Bb. Red blood cell hypochromia
- Cc. Macrocytosis
- Dd. Elliptocytosis
- Ee. Sickle cell disease
634. What is the pathogenetic factor involved in the development of iron deficiency anemia?
- AInflammation of the small intestine with iron malabsorption
- BGastric achlorhydria with reduced iron assimilation from food
- CGastric hyperchlorhydria with destruction and reduced assimilation of iron from food
- DAcute hemorrhagic syndrome with iron loss
- EInflammation of the large intestine with iron malabsorption
735. What is the pathogenetic factor involved in the development of iron deficiency anemia?
- A• Chronic inflammation (causes loss of blood like gastric/duodenal ulcers)
- B• Malnutrition
- C• Gastrectomy
- D• Achlorhydria
- E• Iron binding foods( Eggs, Tea, Coffee )
836. How do mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH) change
in iron deficiency anemia?- AMCV increases; MCH decreases
- BMCV increases; MCH increases
- CMCV decreases; MCH decreases
- DMCV decreases; MCH increases
- EMCV normal; MCH decreases
937. How do mean corpuscular hemoglobin concentration (MCHC) and mean corpuscular
hemoglobin (MCH) change in iron deficiency anemia?- AMCH increases; MCHC decreases
- BMCH increases; MCHC increases
- CMCH decreases; MCHC decreases
- Dnormal MCH; MCHC normal MCV
- Edecreases; MCH decreases
1038. How do mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean
corpuscular hemoglobin concentration (MCHC) change in iron deficiency anemia?- AMCV<80ft, MCH<26pg; MCHC<30 g/dl
- BMCV>100ft, MCH<35pg; MCHC=32 g/dl
- CMCV<80ft; MCH>26pg; MCHC<30 g/dl
- DMCV>100ft; MCH>35pg; MCHC<32 g/dl
- EMCV>100ft; MCH<35pg; MCHC>32 g/dl
1139. How do mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and serum
ferritin change in iron deficiency anemia?- AMCV decreases; MCH decreases; serum ferritin decreases
- BMCV increases; MCH increases; serum ferritin decreases
- CMCV increases; MCH increases; serum ferritin increases
- DMCV decreases; MCH increases; serum ferritin decreases
- EMCV increases; MCH decreases; serum ferritin decreases
1240. How do mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and serum
ferritin change in anemia of chronic inflammation?- AMCV decreases; MCH decreases; serum ferritin decreases
- BMCV increases; MCH increases; serum ferritin decreases
- CMCV increases; MCH increases; serum ferritin increases
- DMCV decreases; MCH increases; serum ferritin decreases
- EMCV decreases; MCH decreases; serum ferritin increases
1341. How do hemoglobin (Hb), mean corpuscular hemoglobin (MCH), and serum ferritin change
in iron deficiency anemia?- AHb decreases; MCH decreases; serum ferritin decreases
- BHb increases; MCH increases; serum ferritin decreases
- CHb increases; MCH increases; serum ferritin increases
- DHb decreases; MCH increases; serum ferritin decreases
- EHb increases; MCH decreases; serum ferritin decrease
1442. How do mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean
corpuscular hemoglobin concentration (MCHC) change in iron deficiency anemia?- AMCV decreases; MCH decreases; MCHC decreases
- BHb increases; MCH increases; MCHC decreases
- CHb increases; MCH increases; MCHC increases
- DHb decreases; MCH increases; MCHC decreases
- EHb increases; MCH decreases; MCHC decreases
1542. How do mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean
corpuscular hemoglobin concentration (MCHC) change in iron deficiency anemia?- AMCV<80ft, MCH<26pg; MCHC<30 g/dl
- BMCV>100ft, MCH<35pg; MCHC=32 g/dl
- CMCV<80ft; MCH>26pg; MCHC<30 g/dl
- DMCV>100ft; MCH>35pg; MCHC<32 g/dl
- EMCV>100ft; MCH<35pg; MCHC>32 g/dl
1642. How do mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean
corpuscular hemoglobin concentration (MCHC) change in iron deficiency anemia?- AMCV < 81 fL: MCH < 26 pg MCHC < 30 g/dl
- BMCV > 81 fL: MCH > 26 pg MCHC >30 g/dl
- CMCV >81 fL: MCH = 30 pg ; MCHC <30 g/dl
- DMCV = 81 fL; MCH > 26 pg : MCHC < 30 g/dl
- EMCV = 110g/l; MCH <26 pg : MCHC > 30 g/dl
1743. What are the hematologic changes in peripheral blood in absolute primary erythrocytosis?
- Aa. granulocytosis
- Bb. erythrocyte count greater than 5.1012/IT
- Cc. reticulocyte count greater than2.5%
- Dd. thrombocytosis
- Ee. reticulocyte count below 0.5%
1844. What are the hematologic changes in peripheral blood in absolute primary erythrocytosis?
- Aa. erythrocyte count 6X106 /mm3
- Bb. hemoglobin level 18 g/dL
- Cc. hemoglobin level 16g/dL
- Dd. reticulocyte count equal to 0.5%
- Ee. normocythemic hypervolemia
1945. What is a hematologic change in peripheral blood in absolute secondary erythrocytosis?
- Aa. hemoglobin content greater than 160 g/L
- Bb. hemoglobin content equal to 150 g/L
- Cc. erythrocyte count equal to 5x1012/L
- Dd. reticulocytes exceed 12‰
- Ee. thrombocytosis
2046. What is the pathogenetic mechanism of absolute primary erythrocytosis? SINGLE OPTION CORRECT
- AHematopoietic bone marrow hyperplasia with unlimited proliferation of myelopoiesis stem cells
- BHematopoietic bone marrow hyperplasia with unlimited proliferation of lymphopoiesis stem cells
- CHematopoietic bone marrow hyperplasia with unlimited proliferation of myeloblasts
- DHematopoietic bone marrow hyperplasia with unlimited proliferation of pluripotent hematopoietic stem cells
- EHematopoietic bone marrow hyperplasia with blockade of myeloblast differentiation
2147. How do circulating blood volume (CBV) and serum iron change in absolute primary
erythrocytosis?- ACBV > 5.5 L; Serum iron < 60 µg/dL
- BCBV<5.5 L; Serum iron<60 µg/dL
- CCBV=5.5 L; Serum iron=60 µg/dL
- DCBV<2.5 L; Serum iron>60 µg/dL
- ECBV>5.5 L; Serum iron>60 µg/d
2249. How do circulating blood volume (CBV) and serum iron change in absolute primary
erythrocytosis?- ACBV increases; serum iron increases
- BCBV decreases; serum iron decreases
- CCBV does not change; serum iron decreases
- DCBV increases; serum iron decreases
- ECBV decreases; serum iron increases
2348. How do circulating blood volume (CBV) and serum iron change in relative erythrocytosis?
- ACBV increases; serum iron increases
- BCBV decreases; serum iron decreases
- CCBV decreases; serum iron doesn’t change
- DCBV increases; serum iron decreases
- ECBV decreases; serum iron increases
2450. How do circulating blood volume (CBV) and serum iron change in absolute secondary
erythrocytosis?- ACBV > 5.5 L; Serum iron < 60 µg/dL
- BCBV<5.5 L; Serum iron<60 µg/dL
- CCBV>5.5 L; Serum iron=60 µg/dL
- DCBV<2.5 L; Serum iron>60 µg/dL
- ECBV>5.5 L; Serum iron>60 µg/dL
2551. How do circulating blood volume (CBV) and serum iron change in relative erythrocytosis?
- ACBV > 5.5 L; Serum iron <60 µg/dL
- BCBV<5.5 L; Serum iron=60 µg/dL
- CCBV>5.5 L; Serum iron=60 µg/dL
- DCBV<2.5 L; Serum iron>60 µg/dL
- ECBV>5.5 L; Serum iron>60 µg/d
2652. Which cells are responsible for the increased hematocrit in patients with absolute primary
erythrocytosis?- AErythrocytes
- BLymphocytes
- CMacrophages
- DEosinophils
- EBasophils
2753. How does erythropoietin level change in absolute primary erythrocytosis?
- AInitially increases, then decreases
- BDoes not change
- CGrows
- DInitially decreases, then increases
- EDecreases
2854. How does erythropoietin level change in absolute secondary erythrocytosis?
- AInitially increases, then decreases
- BDoes not change
- CGrows
- DInitially decreases, then increases
- EDecreases
2955. How does erythropoietin level change in relative erythrocytosis?
- AInitially increases, then decreases
- BDoes not change
- CGrows
- DInitially decreases, then increases
- EDecreases
3056. What clinical manifestations are characteristic in a patient with absolute primary
erythrocytosis disease? ( Basically Vaquez they just got lazy :L)- Aa) Bradycardia
- Bb) Thrombosis
- Cc) Headache
- Dd) Jaundice
- Ee) Pallor
3157. What are the pathophysiologic mechanisms of autoimmune hemolytic anemia?
- AOpsonization of erythrocytes with IgM→complement activation→lysis of
erythrocytes by the membrane attack complex in the bloodstream - BOpsonization of erythrocytes with IgM→complement activation→lysis of
erythrocytes by the complement fraction C3a and C5a in the bloodstream - COpsonization of erythrocytes with IgG→recognition by the Fc fragment of
phagocyte cells→phagocytosis of erythrocytes in the spleen - DOpsonization of erythrocytes with IgM→complement activation→lysis of
erythrocytes by the membrane attack complex in the spleen - EOpsonization of
erythrocytes with IgG→recognition by the Fc fragment of phagocyte cells→lysis
of erythrocytes in the bloodstream
- AOpsonization of erythrocytes with IgM→complement activation→lysis of
3258. What are the biochemical changes in intracellular hemolysis?
- AHyperbilirubinemia with unconjugated fraction
- BIncreased level of haptoglobin in the blood
- CReduced level of free hemoglobin in the blood
- DLow haptoglolbin level in blood
- EHyperbilirubinemia with conjugated fraction
3359. What are the biochemical changes in intravascular hemolysis?
- AHyperbilirubinemia with unconjugated fraction
- BIncreased level of haptoglobin in the blood
- CReduced level of free hemoglobin in the blood
- DIncreased level of free hemoglobin in the blood
- EHyperbilirubinemia with conjugated fraction
3459. What are the biochemical changes in intravascular hemolysis?
- AHepatomegaly
- BIncreased level of free hemoglobin in the blood
- CLow levels of haptoglobin in the blood
- DIncreased haptoglobin level in the blood
- ESplenomegaly
3560. What biochemical change is common for both intravascular and intracellular hemolysis?
- AHyperbilirubinemia with unconjugated fraction
- BIncreased level of haptoglobin in the blood
- CReduced level of free hemoglobin in the blood
- DSplenomegaly
- EHyperbilirubinemia with conjugated fraction
3634. What is the pathogenetic factor involved in the development of iron deficiency anemia?
- AGenetic deficiency of DMT-1 (a divalent metal transporter) and the inability to capture Fe2+ at the enterocyte level
- BGenetic deficiency of DMT-1 (a divalent metal transporter) and the inability to release Fe2+ from the enterocyte into the blood
- CGenetic deficiency of ferroportin and the inability to capture Fe2+ at the enterocyte level
- DGenetic deficiency of ferroportin and the inability to release Fe2+ from the enterocyte into the blood
- EGenetic deficiency of apotransferrin and the inability to release Fe2+ from the enterocyte into the blood
3735. What is the pathogenetic factor involved in the development of iron deficiency anemia?
- AGenetic deficiency of DMT-1 (a divalent metal transporter) and the inability to release Fe2+ from the enterocyte into the blood
- BGenetic deficiency of ferroportin and the inability to capture Fe2+ at the enterocyte level
- CHephaestin deficiency and the inability to oxidize Fe2+ to Fe3+ and its binding to apotransferrin
- DHephaestin deficiency and the inability to oxidize Fe2+ to Fe3+ and its binding to epitheliocytes
- EHepcidin deficiency and the inability to oxidize Fe2+ to Fe3+ and its binding to apotransferrin
3835. What is the pathogenetic factor involved in the development of iron deficiency anemia?
- AGenetic deficiency of apotransferrin and the impossibility of releasing Fe2+ from the enterocyte into the blood
- BGenetic deficiency of transferrin and the impossibility of transporting Fe3+ to the tissues
- CHepcidin deficiency and the impossibility of releasing Fe2+ from the enterocyte into the blood
- DHephaestin deficiency and the impossibility of oxidizing Fe2+ to Fe3+ and its capture at the epitheliocyte level
- EHepcidin deficiency and the impossibility of oxidizing Fe2+ to Fe3+ and its binding to apotransferrin
3937. How do mean corpuscular hemoglobin concentration (MCHC) and mean corpuscular hemoglobin (MCH) change in iron deficiency anemia?
- AMCHC > 35 g/dl
- BMCHC < 30 g/dl
- CMCHC = 33 - 37 g/dl
- DMCH > 35 pg
- EMCH < 27 pg
4038. How do mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) change in iron deficiency anemia?
- AMCV > 100 fl
- BMCV = 80-100 fl
- CMCV < 80 fl
- DMCH > 35 pg
- EMCH < 27 pg
4143. What are the hematologic changes in peripheral blood in absolute primary erythrocytosis?
- Alymphocytosis
- Bthrombocytosis
- Cthrombocytopenia
- Dreticulocyte count above 1.5% reticulocyte
- Eleukopenia
4243. What are the hematologic changes in peripheral blood in absolute primary erythrocytosis?
- AThrombocytosis; granulocytosis; monocytosis
- BGranulocytosis; lymphocytosis; monocytosis
- CThrombocytosis; agranulocytosis; monocytosis
- DThrombocytosis; lymphocytosis; monocytopenia
- EThrombocytosis; lymphocytopenia; monocytosis
4356. What clinical manifestations are characteristic in a patient with absolute primary erythrocytosis disease?
- Aprimary arterial hypertension
- Bsecondary hypertension
- Cprimary arterial hypotension
- Dperipheral cyanosis
- Ejaundice
4457. What are the pathophysiologic mechanisms of autoimmune hemolytic anemia?
- AOpsonization of erythrocytes with IgG - recognition by the Fc fragment of phagocytic cells - extravascular hemolysis
- BOpsonization of erythrocytes with IgM - complement activation - intravascular hemolysis
- COpsonization of erythrocytes with IgG - recognition by the Fc fragment of phagocytic cells - intravascular hemolysis
- DOpsonization of erythrocytes with IgM - complement activation - extravascular hemolysis
- EOpsonization of erythrocytes with IgG - complement activation - extravascular hemolysis
Informationen
- Beschreibung
- Quiz am 31-60 Pathophys sem 6, erstellt von ppppp oooo am 06/03/2026.
- Autor
- ppppp oooo
- Sprache
- English
- Aufrufe
- 48
- Schlagwörter
- Bewertung
- Noch keine Bewertungen Bewerte dieses Quiz