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Calf problems 1

Rachael Jones Reproduction - CVS1 Englisch 100 Karten

Karten in diesem Stapel (100)

  1. 1Give a list of all the calf diseases that can occur.- Stillbirths
    - Critical care of the newborn calf
    - The essential colostrum
    - Systemic infectious problems
    - Infectious diarrhoea problems
    - Non-infectious gastro-intestinal problems
    - Neurological problems
    - Respiratory problems
  2. 2What is the issue to farmers when they have calves born dead?Whether beef or dairy, it is still a loss of money. The farm is a business and so there will be loss of productivity and potential for money
  3. 3What is the most traumatic calf problem for a farmer?Stillbirth - spent money feeding the cow to full term and then the product at the end is dead.
  4. 4Why are calf problems costly to the farmers?Economically, genetics, resources
  5. 5What is the definition of stillbirth?Gestation >260 days i.e. viable. For practical purposes includes deaths to 24 hours after birth. Calves may be stillborn or born weak and die shortly afterwards.
  6. 6What does stillbirths include?- ‘weak calf syndrome’ – calf born alive, either fails to breathe or does so for less than 10 mins
    - ‘lazy calving syndrome’/‘uterine inertia syndrome’ - labour does not progress despite an open cervix and no evidence of clinical hypocalcaemia
  7. 7What is the incidence of stillbirths?Up to 50% of calf deaths in first week
  8. 8Why are stillbirths hidden unquantified losses on many farms?- Not recorded and have:
    1. Direct losses: loss of calf
    2. Indirect losses:
    - retained placenta, metritis, trauma to birth canal, reduced fertility, milk loss
    - veterinary costs
    - death of dam, replacement costs
    - loss of genetic gain
  9. 9What are the causes of stillbirth?- Dystocia/anoxia = most common cause (75%)
    - Infection pre-partum
    - Hypocalcaemia
    - Twinning
    - Iodine deficiency
    - Vitamin E/selenium?
  10. 10Why does dystocia cause stillbirth?- Heifers due to the foetal size
    - Dystocia is common within the herds normally
  11. 11What is uterine inertia syndrome?Lazy calving - poorly understood problem
    - Cervix dilates, the amnion is usually intact but the cow does not proceed to second stage labour. Calf usually born dead or dies shortly afterwards
  12. 12What are the likely infections during parturition?BVD virus, Leptospira hardjo and A.pyogenes
  13. 13What is the effect of having twins on the causes of stillbirth?Three times the stillbirth rate of singles, probably related to prolonged parturition/dystocia
  14. 14Why does iodine deficiency occur as a cause for stillbirth?Seen mostly in heifers (calving in the autumn/winter) that did not receive supplementary feed or minerals during the dry period.
  15. 15What are features of intra-partum deaths?Most have hypoxia lesions (petechial and sometimes ecchymotic haemorrhages in the heart, thymus, epicardium and spleen). Lungs may be atelactic or inflated. Head and neck often swollen (clear s/c oedema) due to vagina constricting venous return from head.
  16. 16What are the main areas of investigation of stillbirths?Multiple areas but the main ones are:
    1. History and available data
    2. PM examination
    3. Clinical pathology
  17. 17What is taken in the history of an investigation of stillbirths?- Quantify:
    - Estimate gestation length
    - Investigate bull relationships
    - Examine supervision and facilities
    - Duration of labour: Normal 2nd stage (cows) is 30mins-4h, most <2h
    - Cow condition score
    - Age of dams
    - Calves born weak?
    - Sex ratio of stillborn. If significantly more male than female, likely to be a bull effect
  18. 18What should be done for clinical pathology of stillbirth investigation?Blood sample 10 cows in late pregnancy for Cu, GSH-Px (for Se), Mg, plasma inorganic iodine (T3/T4 no value)
  19. 19What happens to the cornea following stillbirth?Reduction in intraocular pressure in stillborn calves leads to corneal opacity and indicates the calf has died at least 12 hours before birth.
  20. 20What is special about Charolais stillborn calves in particular?The eye will be sunken into the socket
  21. 21What is an indicator that the calf has been dead a number of days before being delivered?The hair and hooves coming off
  22. 22What does the tongue being out suggest when stillborn?Died during delivery as blood into tongue
  23. 23What is a potential cause for having oedema of the head and neck when stillborn?Umbilical cord around the neck
  24. 24What is milk fever and how does it relate to stillbirth?Hypocalcaemia and results in weak labour and increased likelihood of stillbirth
  25. 25Is milk fever a common cause for stillbirth?Yes - one of teh most common
  26. 26Give a list of preventions of stillbirths.- Multifactorial
    - Bull selection - dystocia history
    - Cow nutrition - aim for BCS of 2.5-3, adequate mineral supply and give iodine
    - Supervision of labour
    - Exercise dams
    - Induction or delay of parturition
    - CCTV - critical care, colostrum feeding
  27. 27Why can managing the time of parturition allow for reduction in stillbirths?- Know when supposed to be delivering and so can support her
    - Induction with corticosteroids or PGs
    - Delay with clenbuterol (Planipart) 10ml at 1800 hrs, 7ml at 2200 hours - no births before 6am
  28. 28What is essential for calving in dairy heifers?- Management of service
    - Management pre-calving
    - Management at calving
  29. 29How should dairy heifers be managed at service?- Ensure service weight is more than 360kg
    - Take care when selecting the service sire – avoid large breeds
  30. 30How should dairy heifers be managed pre-calving?- Adjust feed levels to avoid calving in over-fat condition
    - Restrict energy intake in the last 3 weeks of pregnancy
    - Attention to minerals: I, Se, Mg
    - Exercise
    - Frequent observation
  31. 31How should dairy heifers be managed at calving?- Calve grazed heifers in their field or paddock if possible.
    - Housed heifers should calve in familiar surroundings.
  32. 32What should be provided for the neonate to get it off to a good start?- Resuscitation
    - Colostrum
    - Mothering
    - Hygiene
  33. 33What happens on delivery of the calf in terms of acid-base status?Normal delivery results in a combined respiratory and metabolic acidosis:
    -due to pre- and intra-partum hypoxia.
    - temporary
    - calf has very good compensatory mechanisms
    - has usually compensated by 8 hours post-partum.
  34. 34What happens on abnormal delivery of the calf in terms of acid-base status?Severe acidosis and other clinical signs:
    - apnoea or respiratory distress (shallow abdominal breathing)
    - depression
    - decreased heart rate
    - loss of muscle tone
    - increased interval from delivery to sternal recumbency (normal is 4 plus or minus 2 minutes)
  35. 35What is resuscitation?A combination of physical efforts, mechanical aids and drugs
  36. 36How can an ambu bag be used in resuscitation?Attached to the endotracheal tube and allow breaths to be given
  37. 37What is an important way of resusitating a calf?Removing the mucous out of the trachea and producing a cough reflex
    - Don't leave hanging upside down for too long as pressure on diaphragm reduces the breaths
  38. 38What is acute neonatal respiratory distress syndrome?Decreased levels of surfactant, and severe respiratory distress
  39. 39What are differential diagnosis for acute neonatal respiratory distress syndrome?- Fractured ribs or other trauma preventing negative pressure in the chest and so struggle to breathe
    - inhalation of meconium
    - congenital defects
  40. 40What is meconium in the foetal fluids a sign of?Stress before birth = BAD
  41. 41What are the treatments for acute neonatal respiratory distress syndrome?- Increase O2 - nasal tube
    - Corticosteroids
    - Doxapram
    - (antibiotics)
    - careful nursing including administration of colostrum
  42. 42What is doxapram?Respiratory stimulant - helps inflate the lungs ( inject or on tongue)
  43. 43What is the issue with calves that have respiratory distress?More difficult to get them to take colostrum and so more at risk of getting disease later in life
  44. 44What is a sign that a calf never took a breath?The lungs will sink in water (never been inflated)
  45. 45What is found on histology with neonatal acute respiratory distress syndrome?Hyaline membrane - proteinatious in airway (lack of surfactant and never inflated)
  46. 46What does VSD stand for?Ventricular Septum defect
  47. 47Give a congenital cardiac defect.VSD
  48. 48Give features of VSD.- Most common shunting L to R
    - Stunting
    - Decreased exercise tolerance
    - Listlessness
    - Not cyanosed
    - Systolic murmur on both sides of chest
    - Acute heart failure + pulmonary oedema
    - NORMAL
  49. 49What does the severity of the heart murmur relate to?The size of the hole
    - Big hole = little murmur due to less resistance
  50. 50What is seen with multiple cardiac defects?- Cyanosis
    - Weak
  51. 51What are general points of congenital cardiac defects?- Exacerbates signs of respiratory disease
    - Defective pulmonary circulation (oedema)
    - Murmur
    - Other congenital defects e.g. skeleton
  52. 52What is a ventricular septal defect?The muscular division between the ventricles isn't complete
  53. 53What is tetralogy of Fallot?- Pulmonary stenosis
    - Right ventricular hypertrophy
    - VSD
    - Dextroaorta
    Calf will be very weak and not thrive
  54. 54What is important for a successful calf?Immune transfer in the calf
  55. 55What is colostrum?- A source of energy
    - A source of vitamins and minerals
    - Most importantly a source of antibodies - Only source to newborns
  56. 56For how long are calves able to absorb antibodies?- Absorption by pinocytosis for first 24-36 hours
    - Linear decline in absorption, must first suckle by 6 hrs
  57. 57How does the level of antibodies absorbed relate to the illness in calves?- Approx. 50% UK calves fail to absorb adequate amounts
    - Mortality rate in most neonatal infectious diseases directly linked to hypogammaglobulinaemia
  58. 58Do antibodies replace enteropathogens already attached to intestinal mucosal cells?No
  59. 59What infection is there limited protection against?Enzootic pneumonia - roatvirus
  60. 60What are the factors that affect transfer of colostral antibodies?- Poor maternal nutrition
    - Parity: older cows likely to transfer immunity to a wider range of pathogens
    - Pre-partum leakage/milking
    - Premature calving
    - Movement of dam in late pregnancy: related to previous exposure
    - Interval from calving to removal of calf
    - Maternal and calf behaviour
    - Inadequate mothering
    - Failure of calf to suck
  61. 61What can cause inadequate mothering, leading to colostral antibody transfer being poor?- Inexperience (heifers) or poor maternal bond
    - Failure to locate calf (overcrowded calving pen, darkness)
    - Illness in dam e.g. hypocalcaemia, obdurator paralysis; pendulous udder;
    removal of calf too early
  62. 62Why can the calf fail to suck causing the colostral antibody transfer to be affected?- Weakness or injury from prolonged labour or excessive traction;
    - Congenital abnormalities e.g. contracted tendons;
    - Failure to find dam (one in six cows born in a calving yard sucks the wrong cow first);
    - Removal from dam;
    - Infection very early in life;
    - As ambient temperature falls, interval to first suckling increases.
  63. 63At what stage in development can the foetus respond to antigen?120 days - only chance of producing own antibodies
  64. 64How long does Ig transfer from plasma to colostrum?2 months
  65. 65What is the main Ig in cow colostrum?IgG1
  66. 66What are the non-specific immune factors that are found in colostrum?1. Humoral:
    - Complement
    - Lysozyme
    - Lactoferrin
    - Interferon
    - Acute phase protein
    - Lactoperoxidase
    2. Cellular
    - Neutrophils*
    - Macrophages*
    (* Primary function to protect udder of cow)
  67. 67What are the dam factors that can affect the Ig concentration present in colostrum?1. Yield: increased yield -> increased quality
    2. Parity: heifers have decreased quality and quantity
    3. Breed ? Jersey better than Friesian
    4. Genotype of cow
    5. Age: IgG1 transfer starts earlier in heifers, older cows have increased IgG2 levels
    6. Quarter: increased quality in hind quarters
    7. Twins: no effect
    8. Abortion: decreases quality
  68. 68Why is it not necessarily a good idea to harvest the colostrum from cows that have aborted?Poor quality and potential to carrier infectious agent (could be cause of abortion)
  69. 69What are management factors that affect Ig concentration?1. Time after parturition ~>9 hrs.
    2. Length of dry period
    3. Prepartum milking
    4. Vaccination e.g. “Rotavec Corona, MSD”
    5. Induction
    6. Feeding- no effect on Ig concentration, effects yield
    7. B.C.S. poor condition -> poor quality & quantity
  70. 70What can be used to test the quality of the colostrum?Hydrometer
  71. 71What is considered as colostrum?First milking only
  72. 72How is colostrum absorbed?With a lag period of 2 hours via lymphatics
    - IgG is first and most important and lasts longest
  73. 73At what stage does the calf start producing antibodies to increase the titre?2-3 weeks after birth
  74. 74Is the gut closed off to antibodies after the first 6 hours?No - just its ability to absorb the antibodies is reduced - gut closure starts after birth
  75. 75At what stage are antibodies secreted from the gut?<5 days
  76. 76What is the test for antibodies?1. Zinc sulphate Tubidity test (ZST)
    2. Plasma proteins – should be >5.6g/dl (Refractometry)
    3. Other indirect measures e.g.  GT
  77. 77What is important about when Igs are fed?Synergism between Ig classes in gut, must be fed prior to infection. E. coli adherent to distal S.I. within 3 hrs. of birth, pathological lesions within 12 hrs.
  78. 78What is the normal amount of colostrum for calves to ingest?7-8kg in 24 hours
    - 10% body weight in first 6 hours of life (about 4 litres)
  79. 79What are the 3 Q's related to colostrum?Quality
    Quantity
    Quickly
  80. 80Can colostrum substitutes be used?Yes - but greater volumes are needed to get the same antibody transfer
  81. 81How does the ZST test work?Turbidity of plasma is related to plasma immunoglobulin content when reacted with zinc sulphate. Z.S. turbidity is essentially a measure of IgG.
    However, Z.S.T. levels are a cheap and useful test for immune status and are widely used.
  82. 82What are the outcomes of the ZST test?1. <10 septicaemia/diarrhoea. High mortality
    2. 10 - 20 Diarrhoea. Variable mortality
    3. >20 Healthy/transient diarrhoea
  83. 83What is a colostrometer?- Practical method for rapid determination of colostrum quality prior to feeding newborn calf
    - Measures SG
    - Colour coded scale for quick determination of colostrum quality
  84. 84What are possible colostrum sources?- The dam
    - Other freshly calved cows
    - Stored colostrum
    - Frozen colostrum
    - Freeze dried substitutes
  85. 85Why should you not pool or mix colostrum?Johnes disease
  86. 86Why can't colostrum be stored at room temperature?Colliform production is massive
  87. 87How must you defrost frozen colostrum?Slowly - NOT microwave due to denaturing antibodies
  88. 88How should you manage newborn calves?- Management of dam before calving
    - Management of calving
    - Management of neonate
    - If in doubt, feed colostrum
  89. 89Why is slippery floor a problem for a new born calf?- Problems standing and therefore can't suckle quickly
    - Also tend to be born into pool of slippery amniotic fluid and so struggle to stand
    - Cow may also be recumbent and so harder to locate teh udder
  90. 90What is bovine neonatal pancytopaenia?Connection between BNP and vaccination with an inactivated vaccine against bovine virus diarrhea (BVD) causing alloimmune syndrome.
    - now withdrawn
  91. 91What are features of managing calves more than one day old?- Individual space until weaning
    - No age mixing
    - Clean and dry beds with minimal draughts
    - Avoid high stocking rate
    - Keep adequate number of feeding buckets clean
    - Feed colostrum for up to one week (or longer)
    - Follow manufacturer's instructions
    - Provide pellets and barley straw (or hay)
    - Treat clinical problems promptly
    - Avoid synchronization of stressful procedures
  92. 92What should the maximum age difference be in co-housed calves?2 weeks
  93. 93What does poor calf accommodation relate to in the calf?Hypogammaglobulinaemic
  94. 94Why is having temporary calf accommodation bad?They need to be treated right as are the future of the herd
    - Need to invest
  95. 95What makes a good calf house?- Well ventilated but not drafty
    - Good, deep clean dry bedding
    - Reasonable stocking density
    - Tactile contact with other calves is a UK legal requirement
  96. 96What should happen to the housing between batches?Cleaned and disinfected and bedding kept dry
  97. 97What is a better system for getting calves?Batch rearing i.e. ‘all in - all out’ is better than continually introducing susceptible new calves to the unit
  98. 98What should be used as housing until weaning?Individual pens/igloos with solid partitions - reducing cross infection, inhibit navel sucking and allow individual supervision
  99. 99Why should wooden fences attached together not be used for calf pens?Have no way of letting the calf out when 6 weeks of age, other than to lift over - will be heavy by then
  100. 100What is a healthy sign in calves?Heads down in feed buckets etc.

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Reproduction - CVS1 (Calf medicine - David Barrett) Karteikarten am Calf problems 1, erstellt von Rachael Jones am 07/04/2018.
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