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18522210
FARMACOLOGÍA PROCINÉTICOS
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Flowchart on FARMACOLOGÍA PROCINÉTICOS, created by Maria Gracia Suarez on 20/06/2019.
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metoclopramida
domperidona
cisaprida
mosaprido
Flowchart by
Maria Gracia Suarez
, updated more than 1 year ago
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Created by
Maria Gracia Suarez
almost 5 years ago
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Resource summary
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MECANISMO DE ACCIÓN
AGONISTA 5HT4
ANTAGONISTA 5HT3
ANTAGONISTA D2
Estímulo: distensión
Plexo Mientérico: liberación ACh
Aumenta tono EEI
Aumenta tono y amplitud de contracciones del estómago
Relaja esfínter pilórico
Aumentan peristalsis
Reduce tono basal muscular duodeno
Facilita vaciado gástrico: PROCINÉTICO
Área postrema
Restringe activación Zona Gatillo Quimiorreceptora (ZGT)
Inhibe activación del centro del vómito
ANTIEMÉTICO
Hipófisis
Aumenta secreción prolactina
Glándula mamaria: secreción leche
Estimula lactancia en puerperio
EFECTOS ADVERSOS
Galactorrea
Ginecomastia
Trastornos menstruales
Ganglios basales (Neoestriado)
Bloquea receptores dopa centrales
EFECTOS ADVERSOS
Síndrome Extrapiramidal
Distonía (niños)
Parkinsonismo (ancianos)
Acatisia
Discinesia tardía
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