1108564
Description
Flashcards by jenny schneider, updated more than 1 year ago
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Created by jenny schneider
about 12 years ago
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| Question | Answer |
| What is a solution | a molecular dispersion of two or more components |
| if a drug is dissolved in water, which s the solute and which is the solvent? | drug is solute and water is the solvent |
| besides solid in water, what other types of solutions exist? | gas in liquid liquid in liquid solid in solid |
| What are the three steps in dissolution of solid in liquid? | solute molecule breaks away from lattice cavity must be made in the solvent solute molecule placed in the cavity of the solvent |
| What is a saturated solution? | solute is dissolved at the limit of solubility at a certain temperature |
| what is a supersaturated solution? | supersaturation is a state of a solution that contains more of the dissolved material than could be dissolved by the solvent under normal circumstances |
| True or False if the solute-solvent forces are strong enough to compensate for the forces that are broken, then it is likely that the solid will dissolve in a solvent | True |
| True or False The overall heat exchanged in dissolution process is called entropy | False It is the heat of solution |
| What effect will heating the solvent have on dissolution of a drug which has a negative heat of solution? | less dissolved at higher temperature |
| What effect will heating solvent have when a drug has a positive heat of solution? | it will increase solubility |
| True or False If a drug dissolving in solvent has negative heat of solution, we have an endothermic process | False it is an exothermic process |
| What is the dielectric constant | measure of the influence by the solvent on energy required to separate two oppositely charged bodies |
| Which of the following solvents will have the highest dielectric constant: water alcohol benzene | water as it is the most polar |
| If we have a polar drug, which solvent will it best dissolve in? water or benzene | water |
| Alcohol has a lower dielectric constant than water and is classed as semi-polar solvent True or False | True |
| Write the Noyes-Whitney equation (used to describe rate of dissolution) | dM/dt= DA(Cs-C)/h |
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