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Lymphadenopathy

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Mind Map on Lymphadenopathy, created by spencer.brogan on 10/03/2015.
spencer.brogan
Created by spencer.brogan
spencer.brogan
Created by spencer.brogan over 11 years ago
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Resource summary

Lymphadenopathy
  1. abnormality in the number, size or consistency of lymph nodes.
    1. Causes
      1. Infection (viral, bacterial, fungl, parasitic)
        1. Viral
          1. HIV
            1. URTI
              1. Infectious Mononucleosis
                1. Rubella, varicella, measles
                  1. Hep, A/B
                    1. Dengue fever
                      1. Adenovirus
                        1. Human Herpes virus - 6
                        2. Bacterial
                          1. Septicaemia
                            1. Typhoid fever
                              1. TB
                                1. Syphilis
                                  1. Lyme disease
                                  2. Protozoal
                                    1. toxoplasmosis
                                      1. Chagas disease
                                        1. Sleeping sickness (African trypanosomiasis)
                                        2. Fungal
                                          1. Coccidioidomycosis
                                        3. Neoplastic
                                          1. Acute leukaemia
                                            1. Lymphoma
                                              1. Hodkins/non-hodgkins
                                              2. Neuroblastoma
                                                1. Hystocytoses
                                                2. Inflammatory/ Autoimmune
                                                  1. Heamatological
                                                  2. History:
                                                    1. Infection
                                                      1. Fever
                                                        1. Prior infection (cough, sputem, SOB, pain, redness, discharge, bowels, CNS, headaches, neck stiffness, hotophobia, seazures etc.)
                                                        2. Examination
                                                          1. Infection
                                                            1. Temperature
                                                              1. Haemodynamics (BP, HR, RR, Urine Output)
                                                                1. Conciousness (AVPU, GCS)
                                                                  1. Focused examine for site of origin (chest, abdo etc.)
                                                                    1. Hepatomegly/splenomegaly for malignancy/infection
                                                                    2. Size/No. / site of lymphnodes
                                                                      1. Supraclavicular nodes = malignancy
                                                                        1. Erythema, warmth, fluctuance = lympadenitis
                                                                          1. Firm, non tender, matted together = malignancy
                                                                        3. Investigations
                                                                          1. FBC (incl. blood film, and ESR, plasma viscosity, CRP)
                                                                            1. LFT's
                                                                              1. Swabs
                                                                                1. Depending on Hx
                                                                                  1. Viral titre
                                                                                    1. Epstein-Barr virus
                                                                                      1. HIV
                                                                                        1. Hepatitis
                                                                                        2. Blood cultures
                                                                                          1. Antibodies screen (SLE ant-DSdna ANA, RA ACCP)
                                                                                            1. CXR (sarcoidosis, TB, Malignancy)
                                                                                              1. CT, MRI
                                                                                                1. Fine needle Aspiration
                                                                                              2. Differential Diagnosis
                                                                                                1. Subcutaneous lesion (Lipoma, Abscess)
                                                                                                  1. Hernia
                                                                                                    1. Skin Lesion (Sabaceous cyst)
                                                                                                      1. Neck (thyroid tumour, brachial cleft cyst, Cystic hygromas, Salivary Glands, Thyroglossal duct cysts(often midline))
                                                                                                      2. Management
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