63824
Description
Mind Map by Mahmoud Jeilani, updated more than 1 year ago
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Created by Mahmoud Jeilani
about 12 years ago
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extravasation
- he process of cancer cells leaving a vessel and infiltrating the surrounding tissue.
- . If cancer cells survive the adverse conditions in the vessels and reach the bigger venous blood vessels
- they are carried further by the blood stream and reach, after the passage of the heart, the capillary network of the lung
- there is a high probability that the cancer cells get entangled in the capillary system of the lungs
- This can be explained by the size of the cancer cells (~20 μm diameter) in relation to the capillaries (~3-8 μm diameter).
- cancer discard a great amount of their cytoplasm in order to form smaller, but still vital cells, which can pass the lung capillaries
- When the cancer cells leave the lung capillaries and reach the general arterial vessels, they can migrate into various kinds of body tissue
- extravasation can take place in two different ways.
- One possibility is that cancer cells start to proliferate in the lumen of a vessel
- this could be due Due to the growth of the tumor, the vessel wall is destroyed and thus
the cancer cell's way into the tissue of the organ is paved
- this could be due Due to the growth of the tumor, the vessel wall is destroyed and thus
the cancer cell's way into the tissue of the organ is paved
- second possibility for the cancer cells to penetrate an organ is similar to the intravasation and
includes the degradation of endothelium and basement
- One possibility is that cancer cells start to proliferate in the lumen of a vessel
- extravasation can take place in two different ways.
- When the cancer cells leave the lung capillaries and reach the general arterial vessels, they can migrate into various kinds of body tissue
- cancer discard a great amount of their cytoplasm in order to form smaller, but still vital cells, which can pass the lung capillaries
- This can be explained by the size of the cancer cells (~20 μm diameter) in relation to the capillaries (~3-8 μm diameter).
- there is a high probability that the cancer cells get entangled in the capillary system of the lungs
- they are carried further by the blood stream and reach, after the passage of the heart, the capillary network of the lung
- . If cancer cells survive the adverse conditions in the vessels and reach the bigger venous blood vessels
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