8700918
Description
Mind Map by leen abuafifeh, updated more than 1 year ago
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Created by leen abuafifeh
about 7 years ago
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I always feel tired
- diagnosed with
- Fe deficiency
anemia
- anemia
- Normocytic
- increased destruction
(hemolytic anemia)
- Hereditary
spehrocytosis
- Hereditary
spehrocytosis
- Sickle cell anemia
- Glucose-6-phosphate
dehydrogenase
(G6PD) deficiency
- Paroxysmal
Nocturnal
Hemoglobeinuria
- increased destruction
(hemolytic anemia)
- MCV: >100um3
- Macrocytic
- Megaloblastic
anemia
- VB 12 deficiency
- symptoms of VB12 DEF
- Nerve damage.
- Neurological problems
- Nausea and vomiting
- enlarged liver
- smooth, beefy red tongue
- Nerve damage.
- CAUSES
- vegan
- Impaired absorption
- Intrinsic factor
deficiency (prenicious
anemia- gastrectomy
- Malabsorption
diseases (pancreatic
insufficiency)
- Diffuse intestinal
disease
(lymphoma-Crohn’s
- Competitive parasitic uptake
(tape worm infestation)
- Intrinsic factor
deficiency (prenicious
anemia- gastrectomy
- vegan
- symptoms of VB12 DEF
- folate deficiency
- Increased homocysteine level
- Normal mehylmalonic
acid
- CAUSES
- Dietary deficiency
(alcohol-elderly)
- Increased demand pregnancy-
cancer patients
- Dietary deficiency
(alcohol-elderly)
- Increased homocysteine level
- Impaired DNA synthesis
- Ineffective erythropoiesis
- Ineffective erythropoiesis
- VB 12 deficiency
- Non-megaloblastic anemia
- Alcoholism
- Drugs (Ex- 5 FU)
- Liver disease
- Alcoholism
- Megaloblastic
anemia
- Macrocytic
- SYMPTOMPS OF
ANEMIA
- MCV: <80
- Microcytic
- Anemia of chronic disease
- TB
- Rheumatoid arthritis
- Malignancy
- Chronic alcoholism
- Iron is trapped in BM macrophages
- HEPCIDIN prevents the release of iron
from BM
- decrese EPO production
- Increase in BM iron
stores
- Increase in BM iron
stores
- decrese EPO production
- HEPCIDIN prevents the release of iron
from BM
- TB
- Sideroblastic
- Chronic alcoholism
- VB6 deficiency
- Lead poisoning
- INH therapy
- Hereditary types (x- linked)
- Free iron accumulates inside the
mitochondria (Iron loaded
mitochondria in the bone marrow
erythroblasts)
- RING SIDEROBLASTS
- RING SIDEROBLASTS
- Chronic alcoholism
- Anemia of chronic disease
- Microcytic
- Risk factors
- Women
- Infants and children
- Vegetarians
- Frequent
blood donors
- Women
- Complications
- Heart problems
- Problems during pregnancy
- Growth problems
- Heart problems
- Treatment
- Oral or parenteral iron
preparations
- pyridoxine
- Hydroxyurea
- Pentoxifylline
- Oral or parenteral iron
preparations
- RBC
- HB
- Transport of O2 from lungs to
tissues &CO2 and H+ from tissues
to the lungs for excretion
- HEME
- porphyrin ring with central iron
- . Iron is the site of attachment with O2.
- 4 heme groups
- 4 O2 molecules
- 4 O2 molecules
- Iron
- immune system healthy
- produce the connective tissue
- STORED
- Ferritin
- TRASPORTED
- Transferrin
- Transferrin
- TRASPORTED
- Ferritin
- immune system healthy
- 4 heme groups
- . Iron is the site of attachment with O2.
- porphyrin ring with central iron
- GLOBIN
- HEME
- Transport of O2 from lungs to
tissues &CO2 and H+ from tissues
to the lungs for excretion
- HB
- Normocytic
- Microcytic hypochromic
- C/P
- General features of anemia
- Epithelial atrophy-
Plummer Vinson
syndrome
- Koilonichia
- Pica
- General features of anemia
- C/P
- causes
- increased loss
- dietary deficiency
- increased loss
- anemia
- Fe deficiency
anemia
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