Matthew Coulson
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Microbiology of Genital Tract Infection given by Dr Mooka on 09/11/2018

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Matthew Coulson
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Microbiology of Genital Tract Infection

Question 1 of 40

1

Sexually transmitted diseases can generally also be transmitted via inanimate objects.

Select one of the following:

  • True
  • False

Explanation

Question 2 of 40

1

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The normal vaginal pH is between ( 4-4.5, 8-8.5, 6.5-7.5, 13-13.5 )

Explanation

Question 3 of 40

1

Which of the three following organisms are commensal bacteria in the vagina?

Select one or more of the following:

  • Group B Streptococcus

  • Group C Streptococcus

  • Strep Viridans

  • Staph Aureus

  • Candida

  • Pseudomonas Aeruginosa

  • Haemophilus Influenzae

Explanation

Question 4 of 40

1

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The most common type off Candida is called Candida

Explanation

Question 5 of 40

1

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Candida Albicans is ( more, less ) responsive to treatment than non-candida albicans

Explanation

Question 6 of 40

1

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( Non-Candida Albicans, Candida Albicans ) is rare and usually found in immunosuppressed people

Explanation

Question 7 of 40

1

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Poorly controlled ( diabetes, hypertension, renal impairment, hyperthyroidism ) is a significant risk factor for symptomatic candida albicans infection.

Explanation

Question 8 of 40

1

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Candida Albicans ( is not, is ) typically spread via sexual contact; it ( is not, is ) an STI

Explanation

Question 9 of 40

1

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An uncomplicated Candida Albicans infection should be treated with an antifungal called in the form of a cream to be applied internally.

Explanation

Question 10 of 40

1

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Which type of anaerobic gram positive bacteria, rife in the vagina, utilise glycogen in order to produce lactic acid thus protecting against the growth of infective organisms in the vagina?
bacteria

Explanation

Question 11 of 40

1

Fill the blank space to complete the text.

is a disease of the vagina caused by excessive growth of its commensal bacteria.

Explanation

Question 12 of 40

1

Bacterial Vaginosis is not considered an STI however is more frequently found in women who are sexually active.

Select one of the following:

  • True
  • False

Explanation

Question 13 of 40

1

What is the most common bacterial STI in the UK?

Select one of the following:

  • Chlamydia Trachomatis

  • Neisseria Gonorrhoeae

  • Bacterial Vaginosis

  • Genital Herpes

  • Syphilis

Explanation

Question 14 of 40

1

If a doctor suspected a vaginal infection due to 'a positive whiff test', which infection is most likely present?

Select one of the following:

  • Bacterial Vaginosis

  • Chlamydia Trachomatis

  • Neisseria Gonorrhoeae

  • Syphilis

  • Genital Herpes

Explanation

Question 15 of 40

1

Presentations of Vaginal Infections:
= White creamy discharge often giving off a potent 'fishy' smell
= Usually asymptomatic
= Thin, purulent, yellowish discharge
= Present with a painless ulcer known as a chancre

Drag and drop to complete the text.

    Syphilis
    Neisseria Gonorrhoea
    Chlamydia Trachomatis
    Bacterial Vaginosis

Explanation

Question 16 of 40

1

In the whiff test for bacterial vaginosis, 10% solution of which chemical is added to increase the potency of the smell?

Select one of the following:

  • Potassium Chloride

  • Potassium Hydroxide

  • Potassium Sulphate

  • Potassium Iodide

Explanation

Question 17 of 40

1

Bacterial Vaginosis is mainly associated with which pathogen?

Select one of the following:

  • Gardnerella Vaginalis

  • Peptostreptococcus Anaerobius

  • Fusobacterium Nucleatum

  • Fusobacterium Necrophorum

Explanation

Question 18 of 40

1

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As Bacterial Vaginosis is a anaerobic infection, it is usually treated using which drug?

Explanation

Question 19 of 40

1

Chlamydia has 3 serological groupings:
Serovars A-C =
Serovars D-K =
Serovars L1-L3 =

Drag and drop to complete the text.

    Lymphogranuloma Venereum
    Genital Infection
    Trachoma (non-STI eye infection)

Explanation

Question 20 of 40

1

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The treatment plan for Chlamydia infections is 100mg twice daily for days

Explanation

Question 21 of 40

1

Upon gram staining, chlamydia is typically found to be gram positive.

Select one of the following:

  • True
  • False

Explanation

Question 22 of 40

1

Testing for Chlamydia and Gonorrhoea is done using the same clinical testing. Which 2 of the following investigative modalities are most commonly utilised for these infections?

Select one or more of the following:

  • Combined Nucleic Acid Amplification Tests (NAATs)

  • Polymerase Chain Reaction Testing (PCR)

  • Bacterial Culture testing

  • Blood testing

  • Viral Antigen Detection testing (VAD)

Explanation

Question 23 of 40

1

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Males being tested for chlamydia & gonorrhoea have their ( first-pass urine, mid-stream urine ) tested.
Females being tested for chlamydia & gonorrhoea will have ( a vulvo-vaginal swab, their blood, a mid stream urine sample ) taken.

Explanation

Question 24 of 40

1

Intensely itchy white vaginal discharge tends to be indicative of ...

Select one of the following:

  • Bacterial Vaginosis

  • Candida Albicans Infection

  • Neisseria Gonorrhoeae Infection

  • Chlamydia Trachomatis Infection

Explanation

Question 25 of 40

1

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Neisseria Gonorrhoea is a gram ( negative, positive ) ( intracellular, extracellular ) diplococcus

Explanation

Question 26 of 40

1

Chlamydia Trachomatis infection is much more common than Neisseria Gonorrhoeae infection.

Select one of the following:

  • True
  • False

Explanation

Question 27 of 40

1

Neisseria Gonorrhoea infection of the pharynx is common is women and MSM and is almost always asymptomatic.

Select one of the following:

  • True
  • False

Explanation

Question 28 of 40

1

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All patients with Gonorrhoea infection are now treated in secondary care due to the high incidence of antibiotic resistance. They are treated with ( intramuscular, intravenous, oral, subcutaneous ) ( Ceftriaxone, Azithromycin, Ciprofloxacin )

Explanation

Question 29 of 40

1

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Infection of the prostate (prostatitis) can occur in women and MSM. This typically presents with the same symptoms as a UTI. This is is typically treated by a four week course of the drug ( Ciprofloxacin, Ceftriaxone, Trimethoprim )

Explanation

Question 30 of 40

1

In terms of Syphilis, when the chancre heals this means that the syphilis has cleared and there is no longer an infection present.

Select one of the following:

  • True
  • False

Explanation

Question 31 of 40

1

Tenesmus (and bloody diarrhoea) alongside symptoms of an STI is typically indicative of ...

Select one of the following:

  • Lymphogranuloma Venereum Chlamydia infection

  • Bacterial Vaginosis

  • Syphilis infection

  • Genital Herpes

  • Neisseria Gonorrhoeae infection

Explanation

Question 32 of 40

1

Serological tests for Syphilis:
= Positive for syphilis infection, however not useful in monitoring therapy
= Indicate tissue inflammation, useful for monitoring response to therapy. Usually become negative following syphilis treatment

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    Non-specific tests
    Specific tests

Explanation

Question 33 of 40

1

Serological tests for Syphilis:
Specific Tests =
Non-Specific Tests =

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    E.g. TPPA & TPHA
    E.g. RPR & VDRL

Explanation

Question 34 of 40

1

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( IgM & IgG ELISA, TPPA, TPHA, TPPA & TPHA ) testing is used as the screening test for syphilis and provides a good indicator of early disease.

Explanation

Question 35 of 40

1

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Of the two immunoglobulins in the ELISA syphilis test, ( IgM, IgG ) is the good indicator for early disease

Explanation

Question 36 of 40

1

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Syphilis infection is typically treated by ( Penicillin G, Penicillin D, Penicillin V )

Explanation

Question 37 of 40

1

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Genital Herpes tends to be caused by Herpes Simplex Virus Type ( 2, 1 )

Explanation

Question 38 of 40

1

A person presenting with shallow ulcers around the vagina which are excruciatingly sore are likely to have which of the following conditions?

Select one of the following:

  • Bacterial Vaginosis

  • Genital Herpes

  • Chlamydia Trachomatis infection

  • Neisseria Gonorrhoea infection

  • Syphilis

  • Trichomonas Vaginalis

Explanation

Question 39 of 40

1

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The best investigative test for genital herpes is ( viral PCR, viral culture, NAAT testing )

Explanation

Question 40 of 40

1

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Pubic lice cause the pubic hair on the mons pubis to become intensely itchy. It is typically treated with lotion

Explanation