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Microbiology of Genital Tract Infection

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Microbiology of Genital Tract Infection given by Dr Mooka on 09/11/2018
Matthew Coulson
Quiz by Matthew Coulson, updated more than 1 year ago
Matthew Coulson
Created by Matthew Coulson over 5 years ago
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Resource summary

Question 1

Question
Sexually transmitted diseases can generally also be transmitted via inanimate objects.
Answer
  • True
  • False

Question 2

Question
The normal vaginal pH is between [blank_start]4-4.5[blank_end]
Answer
  • 4-4.5
  • 8-8.5
  • 6.5-7.5
  • 13-13.5

Question 3

Question
Which of the three following organisms are commensal bacteria in the vagina?
Answer
  • Group B Streptococcus
  • Group C Streptococcus
  • Strep Viridans
  • Staph Aureus
  • Candida
  • Pseudomonas Aeruginosa
  • Haemophilus Influenzae

Question 4

Question
The most common type off Candida is called Candida [blank_start]Albicans[blank_end]
Answer
  • Albicans

Question 5

Question
Candida Albicans is [blank_start]more[blank_end] responsive to treatment than non-candida albicans
Answer
  • more
  • less

Question 6

Question
[blank_start]Non-Candida Albicans[blank_end] is rare and usually found in immunosuppressed people
Answer
  • Non-Candida Albicans
  • Candida Albicans

Question 7

Question
Poorly controlled [blank_start]diabetes[blank_end] is a significant risk factor for symptomatic candida albicans infection.
Answer
  • diabetes
  • hypertension
  • renal impairment
  • hyperthyroidism

Question 8

Question
Candida Albicans [blank_start]is not[blank_end] typically spread via sexual contact; it [blank_start]is not[blank_end] an STI
Answer
  • is not
  • is
  • is not
  • is

Question 9

Question
An uncomplicated Candida Albicans infection should be treated with an antifungal called [blank_start]Clotrimazole[blank_end] in the form of a cream to be applied internally.
Answer
  • Clotrimazole

Question 10

Question
Which type of anaerobic gram positive bacteria, rife in the vagina, utilise glycogen in order to produce lactic acid thus protecting against the growth of infective organisms in the vagina? [blank_start]Lactobacillus[blank_end] bacteria
Answer
  • Lactobacillus

Question 11

Question
[blank_start]Bacterial vaginosis[blank_end] is a disease of the vagina caused by excessive growth of its commensal bacteria.
Answer
  • Bacterial vaginosis

Question 12

Question
Bacterial Vaginosis is not considered an STI however is more frequently found in women who are sexually active.
Answer
  • True
  • False

Question 13

Question
What is the most common bacterial STI in the UK?
Answer
  • Chlamydia Trachomatis
  • Neisseria Gonorrhoeae
  • Bacterial Vaginosis
  • Genital Herpes
  • Syphilis

Question 14

Question
If a doctor suspected a vaginal infection due to 'a positive whiff test', which infection is most likely present?
Answer
  • Bacterial Vaginosis
  • Chlamydia Trachomatis
  • Neisseria Gonorrhoeae
  • Syphilis
  • Genital Herpes

Question 15

Question
Presentations of Vaginal Infections: [blank_start]Bacterial Vaginosis[blank_end] = White creamy discharge often giving off a potent 'fishy' smell [blank_start]Chlamydia Trachomatis[blank_end] = Usually asymptomatic [blank_start]Neisseria Gonorrhoea[blank_end] = Thin, purulent, yellowish discharge [blank_start]Syphilis[blank_end] = Present with a painless ulcer known as a chancre
Answer
  • Syphilis
  • Neisseria Gonorrhoea
  • Chlamydia Trachomatis
  • Bacterial Vaginosis

Question 16

Question
In the whiff test for bacterial vaginosis, 10% solution of which chemical is added to increase the potency of the smell?
Answer
  • Potassium Chloride
  • Potassium Hydroxide
  • Potassium Sulphate
  • Potassium Iodide

Question 17

Question
Bacterial Vaginosis is mainly associated with which pathogen?
Answer
  • Gardnerella Vaginalis
  • Peptostreptococcus Anaerobius
  • Fusobacterium Nucleatum
  • Fusobacterium Necrophorum

Question 18

Question
As Bacterial Vaginosis is a anaerobic infection, it is usually treated using which drug? [blank_start]Metronidazole[blank_end]
Answer
  • Metronidazole

Question 19

Question
Chlamydia has 3 serological groupings: Serovars A-C = [blank_start]Trachoma (non-STI eye infection)[blank_end] Serovars D-K = [blank_start]Genital Infection[blank_end] Serovars L1-L3 = [blank_start]Lymphogranuloma Venereum[blank_end]
Answer
  • Lymphogranuloma Venereum
  • Genital Infection
  • Trachoma (non-STI eye infection)

Question 20

Question
The treatment plan for Chlamydia infections is 100mg [blank_start]Doxycycline[blank_end] twice daily for [blank_start]7[blank_end] days
Answer
  • Doxycycline
  • 7

Question 21

Question
Upon gram staining, chlamydia is typically found to be gram positive.
Answer
  • True
  • False

Question 22

Question
Testing for Chlamydia and Gonorrhoea is done using the same clinical testing. Which 2 of the following investigative modalities are most commonly utilised for these infections?
Answer
  • Combined Nucleic Acid Amplification Tests (NAATs)
  • Polymerase Chain Reaction Testing (PCR)
  • Bacterial Culture testing
  • Blood testing
  • Viral Antigen Detection testing (VAD)

Question 23

Question
Males being tested for chlamydia & gonorrhoea have their [blank_start]first-pass urine[blank_end] tested. Females being tested for chlamydia & gonorrhoea will have [blank_start]a vulvo-vaginal swab[blank_end] taken.
Answer
  • a vulvo-vaginal swab
  • their blood
  • a mid stream urine sample
  • first-pass urine
  • mid-stream urine

Question 24

Question
Intensely itchy white vaginal discharge tends to be indicative of ...
Answer
  • Bacterial Vaginosis
  • Candida Albicans Infection
  • Neisseria Gonorrhoeae Infection
  • Chlamydia Trachomatis Infection

Question 25

Question
Neisseria Gonorrhoea is a gram [blank_start]negative[blank_end] [blank_start]intracellular[blank_end] diplococcus
Answer
  • negative
  • positive
  • intracellular
  • extracellular

Question 26

Question
Chlamydia Trachomatis infection is much more common than Neisseria Gonorrhoeae infection.
Answer
  • True
  • False

Question 27

Question
Neisseria Gonorrhoea infection of the pharynx is common is women and MSM and is almost always asymptomatic.
Answer
  • True
  • False

Question 28

Question
All patients with Gonorrhoea infection are now treated in secondary care due to the high incidence of antibiotic resistance. They are treated with [blank_start]intramuscular[blank_end] [blank_start]Ceftriaxone[blank_end]
Answer
  • intramuscular
  • intravenous
  • oral
  • subcutaneous
  • Ceftriaxone
  • Azithromycin
  • Ciprofloxacin

Question 29

Question
Infection of the prostate (prostatitis) can occur in women and MSM. This typically presents with the same symptoms as a UTI. This is is typically treated by a four week course of the drug [blank_start]Ciprofloxacin[blank_end]
Answer
  • Ciprofloxacin
  • Ceftriaxone
  • Trimethoprim

Question 30

Question
In terms of Syphilis, when the chancre heals this means that the syphilis has cleared and there is no longer an infection present.
Answer
  • True
  • False

Question 31

Question
Tenesmus (and bloody diarrhoea) alongside symptoms of an STI is typically indicative of ...
Answer
  • Lymphogranuloma Venereum Chlamydia infection
  • Bacterial Vaginosis
  • Syphilis infection
  • Genital Herpes
  • Neisseria Gonorrhoeae infection

Question 32

Question
Serological tests for Syphilis: [blank_start]Specific tests[blank_end] = Positive for syphilis infection, however not useful in monitoring therapy [blank_start]Non-specific tests[blank_end] = Indicate tissue inflammation, useful for monitoring response to therapy. Usually become negative following syphilis treatment
Answer
  • Non-specific tests
  • Specific tests

Question 33

Question
Serological tests for Syphilis: Specific Tests = [blank_start]E.g. TPPA & TPHA[blank_end] Non-Specific Tests = [blank_start]E.g. RPR & VDRL[blank_end]
Answer
  • E.g. TPPA & TPHA
  • E.g. RPR & VDRL

Question 34

Question
[blank_start]IgM & IgG ELISA[blank_end] testing is used as the screening test for syphilis and provides a good indicator of early disease.
Answer
  • IgM & IgG ELISA
  • TPPA
  • TPHA
  • TPPA & TPHA

Question 35

Question
Of the two immunoglobulins in the ELISA syphilis test, [blank_start]IgM[blank_end] is the good indicator for early disease
Answer
  • IgM
  • IgG

Question 36

Question
Syphilis infection is typically treated by [blank_start]Penicillin G[blank_end]
Answer
  • Penicillin G
  • Penicillin D
  • Penicillin V

Question 37

Question
Genital Herpes tends to be caused by Herpes Simplex Virus Type [blank_start]2[blank_end]
Answer
  • 2
  • 1

Question 38

Question
A person presenting with shallow ulcers around the vagina which are excruciatingly sore are likely to have which of the following conditions?
Answer
  • Bacterial Vaginosis
  • Genital Herpes
  • Chlamydia Trachomatis infection
  • Neisseria Gonorrhoea infection
  • Syphilis
  • Trichomonas Vaginalis

Question 39

Question
The best investigative test for genital herpes is [blank_start]viral PCR[blank_end]
Answer
  • viral PCR
  • viral culture
  • NAAT testing

Question 40

Question
Pubic lice cause the pubic hair on the mons pubis to become intensely itchy. It is typically treated with [blank_start]Malathion[blank_end] lotion
Answer
  • Malathion
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