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Medicine Immunology Quiz on Clinical Immunology Test 2- PMU, created by Med Student on 11/04/2019.

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Clinical Immunology Test 2- PMU

Question 1 of 32

1

The lymphoid inflitration of thyroidea is typical for

Select one of the following:

  • Hashimoto's Thyroiditis

  • Euthroid struma

  • Hemolytic anemia

  • Tuberculosis

Explanation

Question 2 of 32

1

Which method is not useful for detection of specific IgE?

Select one of the following:

  • imumonoenzyme techniques (ELISA. immuno blot)

  • classic reactions (agglutination, precipitation)

  • flowcytometry

  • chemiluminescence

Explanation

Question 3 of 32

1

I type allergic reactions are

Select one of the following:

  • immuno-complex

  • cytotoxic

  • IgE mediated

  • cell mediated

Explanation

Question 4 of 32

1

Monoclonal antibodies connected with diphtheria toxin could be used for

Select one of the following:

  • tumor diagnosis

  • immunostimulation

  • immunosuppressive therapy

  • immunotherapy for tumors

Explanation

Question 5 of 32

1

Select from the dropdown lists to complete the text.

Connect with arrows autoimmune diseases from the left side with relevant characteristics from the right side: wide with relevant characteristics
a. Multiple sclerosis ( 6, 5, 4, 3, 2, 1 )
b. SLE ( 4, 1, 2, 3, 5, 6 )
c. Myasthenia gravis ( 5, 1, 2, 3, 4, 6 )
d. Pernicious anemia ( 1, 2, 3, 4, 5, 6 )
e. Hashimoto thyoiditis ( 2, 1, 3, 4, 5, 6 )
f. Hemolytic anemia ( 3, 1, 2, 4, 5, 6 )

1. autoantibodies against parietal cells of stomach ans intrinsic factor and as a result of this doesn't absorb Vitamin B12
2. autoantibodies against thyroglobuline and thyroid peroxidase
3. antibodies against epitopes of red blood cells
4. antibodies against nucleus antigens
5. antibodies against acetylcholine
6. antibodies against morbidly antigens in liquor and serum, depressed reactions of delayed type hypersensitivity against measles antigens

Explanation

Question 6 of 32

1

Which of the following human tumor antigens are connected with melanoma malignuum?

Select one or more of the following:

  • CA 15-3

  • gp 1900

  • MART-1 Melan A

  • gp 120

Explanation

Question 7 of 32

1

Type II allergic reactions are realized through

Select one of the following:

  • anaphylaxis

  • complement-mediated cytolysis

  • immune complexes

  • infectious immunity

Explanation

Question 8 of 32

1

EBV can cause development of

Select one or more of the following:

  • hepatoma

  • nasopharyngeal carcinoma

  • the Burkitt lymphoma

  • adenocarcinoma pulmonis

Explanation

Question 9 of 32

1

Anaphylactic reactions

Select one of the following:

  • are developed in very short time - 30 min

  • can be followed by inflammatory complication some hours later

  • are result of release of active mediators

  • all answers are correct

Explanation

Question 10 of 32

1

Autoimmune diseases due to antibodies could be a result of:
(mark the wrong answer)

Select one of the following:

  • generation of antigen-antibody complexes

  • antibody-induced complement mediated cytolysis

  • antibodies that inhibit cell receptor

  • cell-mediated reaction

Explanation

Question 11 of 32

1

The Bence-Jones protein can be find mostly in

Select one of the following:

  • urine and serum

  • liquor

  • joint puncture

  • tumor biopsy

Explanation

Question 12 of 32

1

Immuno - scintigraphy uses monoclonal antibodies against tumor antigens connected with

Select one of the following:

  • FITC

  • Rodamine

  • Iodine-131, technetium

  • Enzyme

Explanation

Question 13 of 32

1

What as it we can use as a substrate for detecting of antinuclear antibodies with IFA

Select one or more of the following:

  • rat liver

  • rat kidney

  • rat stomach

  • HEp2 cell line

Explanation

Question 14 of 32

1

Fill the blank spaces to complete the text.

Point two diseases where we can use the Mantoux reaction

Explanation

Question 15 of 32

1

CA-15-3 is a marker for first choice in diagnosis of:

Select one of the following:

  • Hepatoma

  • Ca glandulae mamme

  • Melanoma malignum

  • Astrocytoma

Explanation

Question 16 of 32

1

III type allergic reaction is developed through

Select one of the following:

  • SLE

  • Rheumatoid arthritis

  • Contact dermatitis

  • Acute rheumatism

Explanation

Question 17 of 32

1

The blocking factors secreted from tumor cells during tumor growth

Select one of the following:

  • stop cell growth of tumor cells

  • stop the action of Tc-lymphocytes onto tumor cells

  • stop stimulation of tumor specific B-cells

  • are connected with T-lymphocytes and lead to lysis of tumor cells

Explanation

Question 18 of 32

1

Systemic lupus erythematodes

Select one or more of the following:

  • is caused by mutation in dsDNA

  • is an example of T mediated disease

  • is manifested with many symptoms and affect many organs

  • is a result of forming of immune complexes

Explanation

Question 19 of 32

1

The atopic diseases are developed because:

Select one of the following:

  • often contacts with allergen

  • they are inheritable

  • they are developed due to immune complexes

  • of IgE

Explanation

Question 20 of 32

1

We find autoantibodies against cytotoxic antigens of neutrophils (ANCA) mainly in

Select one of the following:

  • the Goodpasture syndrome

  • amyloidodis

  • granulomatosis of Wegener

  • none of this

Explanation

Question 21 of 32

1

The Bence-Jones protein is

Select one of the following:

  • free heavy chains

  • free light κ or λ chains, imperceptible with electrophoresis

  • autoantibodies from IgM class against normal antibodies (IgG) in patients with rheumatoid arthritis

  • fc fragment of complement

Explanation

Question 22 of 32

1

CEA is increased in

Select one or more of the following:

  • nasopharyngeal carcinoma

  • lymphoma Burkitt

  • gastrointestinal tumors

  • smokers

Explanation

Question 23 of 32

1

The most used techniques for detection of antinuclear antibodies antibodies are

Select one or more of the following:

  • direct immmunofluocrescent test

  • indirect immunofluorescent test

  • agglutination

  • neutralization

  • reaction for

  • ELISA

Explanation

Question 24 of 32

1

How fast is the reaction in cases of type 1 hypersensitivity?

Select one of the following:

  • after 15-30 minutes

  • after 48 hours

Explanation

Question 25 of 32

1

The most frequent biological carcinogens are

Select one of the following:

  • Mycoplasmas

  • Chlamydia

  • DNA- viruses

  • RNA- viruses

Explanation

Question 26 of 32

1

Select from the dropdown lists to complete the text.

Connect with arrows allergic diseases with relevant type allergic reaction
a. Type I ( 3, 1, 2, 4 )
b. Type II ( 4, 1, 2, 3 )
c. Type III ( 1, 2, 3, 4 )
d. Type IV ( 2, 1, 3, 4 )

1. serum disease
2. contact dermatitis
3. anaphylaxis
4. hemolytic disease of the newborn

Explanation

Question 27 of 32

1

Glomerutonephritis and vessel diseases due to antibodies are typical for

Select one of the following:

  • the Arthus Phenomenon

  • edema angioneuroutic

  • SLE

  • anaemia haemolytica

Explanation

Question 28 of 32

1

Anti-mitochondrial antibodies are mostly

Select one of the following:

  • detected in patients with primary biliary cirrhosis

  • detected in patients with rheumatoid arthritis

  • do not harm the organism

Explanation

Question 29 of 32

1

In case of Ca glandulae prostate is increased the serum levels of

Select one of the following:

  • PSA (prostate specific antigen)

  • Antibodies against H.pylori

  • Calcitonin

  • Progesterone

Explanation

Question 30 of 32

1

Auto antibodies against microsomes of thyroid cells can be detected in case of

Select one of the following:

  • Ca gl. thyroidae

  • Ca renis

  • Pancreatitis

  • Ca pancrei

Explanation

Question 31 of 32

1

Autoimmune hemolytic anemia in developed mostly via

Select one of the following:

  • Type I allergic reactions

  • Type II allergic reactions

  • Type III allergic reactions

  • Type IV allergic reactions

Explanation

Question 32 of 32

1

Rheumatoid factor from the serum of patients with rheumatoid arthritis is

Select one of the following:

  • IgM reacting with Fc fragment of endogenous IgG

  • IgM reacting wit Fab fragment of IgG

  • IgE reacting with bacterial antigens

  • Acute-phase proteins

Explanation

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