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Clinical Immunology Test 2- PMU

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Medicine Immunology Quiz on Clinical Immunology Test 2- PMU, created by Med Student on 04/11/2019.
Med Student
Quiz by Med Student , updated more than 1 year ago
Med Student
Created by Med Student about 5 years ago
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Resource summary

Question 1

Question
The lymphoid inflitration of thyroidea is typical for
Answer
  • Hashimoto's Thyroiditis
  • Euthroid struma
  • Hemolytic anemia
  • Tuberculosis

Question 2

Question
Which method is not useful for detection of specific IgE?
Answer
  • imumonoenzyme techniques (ELISA. immuno blot)
  • classic reactions (agglutination, precipitation)
  • flowcytometry
  • chemiluminescence

Question 3

Question
I type allergic reactions are
Answer
  • immuno-complex
  • cytotoxic
  • IgE mediated
  • cell mediated

Question 4

Question
Monoclonal antibodies connected with diphtheria toxin could be used for
Answer
  • tumor diagnosis
  • immunostimulation
  • immunosuppressive therapy
  • immunotherapy for tumors

Question 5

Question
Connect with arrows autoimmune diseases from the left side with relevant characteristics from the right side: wide with relevant characteristics a. Multiple sclerosis [blank_start]6[blank_end] b. SLE [blank_start]4[blank_end] c. Myasthenia gravis [blank_start]5[blank_end] d. Pernicious anemia [blank_start]1[blank_end] e. Hashimoto thyoiditis [blank_start]2[blank_end] f. Hemolytic anemia [blank_start]3[blank_end] 1. autoantibodies against parietal cells of stomach ans intrinsic factor and as a result of this doesn't absorb Vitamin B12 2. autoantibodies against thyroglobuline and thyroid peroxidase 3. antibodies against epitopes of red blood cells 4. antibodies against nucleus antigens 5. antibodies against acetylcholine 6. antibodies against morbidly antigens in liquor and serum, depressed reactions of delayed type hypersensitivity against measles antigens
Answer
  • 6
  • 5
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  • 1
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  • 5
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  • 3
  • 1
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Question 6

Question
Which of the following human tumor antigens are connected with melanoma malignuum?
Answer
  • CA 15-3
  • gp 1900
  • MART-1 Melan A
  • gp 120

Question 7

Question
Type II allergic reactions are realized through
Answer
  • anaphylaxis
  • complement-mediated cytolysis
  • immune complexes
  • infectious immunity

Question 8

Question
EBV can cause development of
Answer
  • hepatoma
  • nasopharyngeal carcinoma
  • the Burkitt lymphoma
  • adenocarcinoma pulmonis

Question 9

Question
Anaphylactic reactions
Answer
  • are developed in very short time - 30 min
  • can be followed by inflammatory complication some hours later
  • are result of release of active mediators
  • all answers are correct

Question 10

Question
Autoimmune diseases due to antibodies could be a result of: (mark the wrong answer)
Answer
  • generation of antigen-antibody complexes
  • antibody-induced complement mediated cytolysis
  • antibodies that inhibit cell receptor
  • cell-mediated reaction

Question 11

Question
The Bence-Jones protein can be find mostly in
Answer
  • urine and serum
  • liquor
  • joint puncture
  • tumor biopsy

Question 12

Question
Immuno - scintigraphy uses monoclonal antibodies against tumor antigens connected with
Answer
  • FITC
  • Rodamine
  • Iodine-131, technetium
  • Enzyme

Question 13

Question
What as it we can use as a substrate for detecting of antinuclear antibodies with IFA
Answer
  • rat liver
  • rat kidney
  • rat stomach
  • HEp2 cell line

Question 14

Question
Point two diseases where we can use the Mantoux reaction [blank_start]Leprosy[blank_end] [blank_start]Tuberculosis[blank_end]
Answer
  • Leprosy
  • Tuberculosis

Question 15

Question
CA-15-3 is a marker for first choice in diagnosis of:
Answer
  • Hepatoma
  • Ca glandulae mamme
  • Melanoma malignum
  • Astrocytoma

Question 16

Question
III type allergic reaction is developed through
Answer
  • SLE
  • Rheumatoid arthritis
  • Contact dermatitis
  • Acute rheumatism

Question 17

Question
The blocking factors secreted from tumor cells during tumor growth
Answer
  • stop cell growth of tumor cells
  • stop the action of Tc-lymphocytes onto tumor cells
  • stop stimulation of tumor specific B-cells
  • are connected with T-lymphocytes and lead to lysis of tumor cells

Question 18

Question
Systemic lupus erythematodes
Answer
  • is caused by mutation in dsDNA
  • is an example of T mediated disease
  • is manifested with many symptoms and affect many organs
  • is a result of forming of immune complexes

Question 19

Question
The atopic diseases are developed because:
Answer
  • often contacts with allergen
  • they are inheritable
  • they are developed due to immune complexes
  • of IgE

Question 20

Question
We find autoantibodies against cytotoxic antigens of neutrophils (ANCA) mainly in
Answer
  • the Goodpasture syndrome
  • amyloidodis
  • granulomatosis of Wegener
  • none of this

Question 21

Question
The Bence-Jones protein is
Answer
  • free heavy chains
  • free light κ or λ chains, imperceptible with electrophoresis
  • autoantibodies from IgM class against normal antibodies (IgG) in patients with rheumatoid arthritis
  • fc fragment of complement

Question 22

Question
CEA is increased in
Answer
  • nasopharyngeal carcinoma
  • lymphoma Burkitt
  • gastrointestinal tumors
  • smokers

Question 23

Question
The most used techniques for detection of antinuclear antibodies antibodies are
Answer
  • direct immmunofluocrescent test
  • indirect immunofluorescent test
  • agglutination
  • neutralization
  • reaction for
  • ELISA

Question 24

Question
How fast is the reaction in cases of type 1 hypersensitivity?
Answer
  • after 15-30 minutes
  • after 48 hours

Question 25

Question
The most frequent biological carcinogens are
Answer
  • Mycoplasmas
  • Chlamydia
  • DNA- viruses
  • RNA- viruses

Question 26

Question
Connect with arrows allergic diseases with relevant type allergic reaction a. Type I [blank_start]3[blank_end] b. Type II [blank_start]4[blank_end] c. Type III [blank_start]1[blank_end] d. Type IV [blank_start]2[blank_end] 1. serum disease 2. contact dermatitis 3. anaphylaxis 4. hemolytic disease of the newborn
Answer
  • 3
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Question 27

Question
Glomerutonephritis and vessel diseases due to antibodies are typical for
Answer
  • the Arthus Phenomenon
  • edema angioneuroutic
  • SLE
  • anaemia haemolytica

Question 28

Question
Anti-mitochondrial antibodies are mostly
Answer
  • detected in patients with primary biliary cirrhosis
  • detected in patients with rheumatoid arthritis
  • do not harm the organism

Question 29

Question
In case of Ca glandulae prostate is increased the serum levels of
Answer
  • PSA (prostate specific antigen)
  • Antibodies against H.pylori
  • Calcitonin
  • Progesterone

Question 30

Question
Auto antibodies against microsomes of thyroid cells can be detected in case of
Answer
  • Ca gl. thyroidae
  • Ca renis
  • Pancreatitis
  • Ca pancrei

Question 31

Question
Autoimmune hemolytic anemia in developed mostly via
Answer
  • Type I allergic reactions
  • Type II allergic reactions
  • Type III allergic reactions
  • Type IV allergic reactions

Question 32

Question
Rheumatoid factor from the serum of patients with rheumatoid arthritis is
Answer
  • IgM reacting with Fc fragment of endogenous IgG
  • IgM reacting wit Fab fragment of IgG
  • IgE reacting with bacterial antigens
  • Acute-phase proteins
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