Daniel Mosele
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DVM1 Veterinary Bioscience: Cells to Systems (Theme 7: Cell Communication - Electrical) Quiz on Lecture 23 Cardiac and Smooth Muscle, created by Daniel Mosele on 02/06/2016.

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Daniel Mosele
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Lecture 23 Cardiac and Smooth Muscle

Question 1 of 10

4

Which of the following is true of both Skeletal and Smooth Muscle

Select one or more of the following:

  • Presence of the Neuromuscular Junction

  • Phosphorylation of Myosin during the Crossbridge Cycle

  • Presence of both Thick and Thin myofilaments

  • Presence of Troponin

  • Presence of Actin

  • Acetylcholine is involved

  • Calmodulin Complex

  • Crossbridge Cycle triggered by an increase in Intracellular Calcium

  • Hormones are involved in the activation

  • Noradrenaline is invovled

Explanation

Question 2 of 10

4

In Comparison to Skeletal Muscle, Cardiac Muscle cells:

Select one or more of the following:

  • Have Less Nuclei

  • Have More Nuclei

  • Have Longer Action Potentials

  • Have Shorter Action Potentials

  • Involve Phosphorylation of Myosin, instead of altering the shape of troponin and position of tropomyosin to reveal a binding site

  • Are More branch-like

  • Are More linear

  • Have Intercalated Discs

  • Do not have Intercalacted Discs

  • Contraction is triggered by the release of Intracellular Calcium, not extracellular Calcium

Explanation

Question 3 of 10

10

Select from the dropdown lists to complete the text.

( Pacemaker Cells, Purkinje Fibres, Sympathetic Nerves, Alpha Motor Neurons, Cardiomyocytes ) in the Heart releases an Action Potential, these spread across the heart. ( Purkinje Fibres, Pacemaker Cells, Cardiomyocytes, Sympathetic Nerves, Adrenaline, Extracellular Calcium, Noradrenaline, GAP Junctions, Desmosomes ) help enhance the spread of the action potential. When the action potential spreads across the cell membrane of individual cardiacmyocytes they invade ( T tubules, D Tubules, M Tubules, C Tubules, S Tubules ) (invaginations in the membrane). These cause the opening of ( Voltage Gated Calcium Channels, Voltage Gated Sodium Channels, Voltage Gated Potassium Channels, Voltage Gated Chloride Channels, Ligand Gated Calcium Channels, Ligand Gated Chloride Channels, Ligand Gated Potassium Channels, Ligand Gated Sodium Channels ). ( Extracellular Calcium, Extracellular Sodium, Extracellular Chloride, Extracellular Potassium, Intracellular Calcium, Intracellular Sodium, Intracellular Chloride, Intracellular Potassium ) then moves into the cytosol. The presence of ( Calcium, Sodium, ATP, Potassium, Chloride, Calmodulin, Acetylcholine, Noradrenaline ) in the cytosol causes further release of ( Calcium from the Sarcoplasmic Reticulum, Calcium from Vesicles, Calcium from the Interstitial Space, Sodium from the Sarcoplasmic Reticulum, Sodium from Vesicles, Sodium from the Interstitial Space ). This phenomenon is termed ( Calcium Dependent Chloride Release, Calcium Dependent Sodium Release, Sodium Dependent Calcium Release, Calcium Dependent Calcium Release, Chloride Dependent Calcium Release, Sodium Dependant Potassium Release, Potassium Dependant Calcium Release ). This results in ( Systole, Diastole ). Strength/Force of Contraction can be modulated by the concentration of ( Extracellular Calcium., Extracellular Potassium, Extracellular Chloride, Extracellular Sodium, Intracellular Calcium, Intracellular Potassium, Intracellular Chloride, Intracellular Sodium )

Explanation

Question 4 of 10

1

With regards to the Transverse Region of Intercalated Discs, which of the following is false?

Select one of the following:

  • A: Align with the Z Line

  • B: Contain Desmosomes

  • C: Aid in Mechanical Cohesion

  • D: Rich in GAP Junctions

  • E: None of the Above

Explanation

Question 5 of 10

1

In Smooth Muscle Myosin heads are present along the entire length of the thick filament

Select one of the following:

  • True
  • False

Explanation

Question 6 of 10

4

Which of the following Statements regarding Smooth Muscle is correct?

Select one or more of the following:

  • T Tubules are present

  • Sarcoplasmic Reticulum is rudimentary

  • Caveoli are present

  • Actin filaments are attached to Dense Bodies

  • Myosin filaments are attached to Dense Bodies

  • Desmin forms a diagonal network across the cell membrane

  • When Myosin filaments contract they pul on Dense Bodies, and everything is pulled together

  • When Actin filaments contract they pull on Dense Bodies, and everything is pulled together

  • All Smooth Muscle most be directly stimulated

  • GAP Junctions are present in all smooth muscle tissue

Explanation

Question 7 of 10

4

Multi-unit Smooth Muscle has

Select one or more of the following:

  • Few GAP Junctions

  • Many GAP Junctions

  • Present in the Large Airways of the Lungs

  • Present in the Ciliary Muscle of the Eye

  • Present in the Wall of the Uterus

  • Present in the Wall of the Jejenum

  • Multiple adherence points (Desmosomes)

  • Poor response to Stretch

  • Discrete points of Innervation

  • Direct stimulation only present in a few cells

Explanation

Question 8 of 10

1

Single Unit Smooth Muscle contraction can be innervated/affected by

Select one of the following:

  • Hormones

  • Neural Input

  • pH

  • Oxygen Levels

  • Body Temperature

  • All of the Above

  • Hormones and Neural Input Only

Explanation

Question 9 of 10

1

ATP is essential in Smooth Muscle, but has a different role to that of Skeletal Muscle. ATP is required as a substrate for Myosin Light Chain Kinase in the phosphorylation of Myosin Cross Bridges.

Select one of the following:

  • True
  • False

Explanation

Question 10 of 10

1

Smooth Muscle, like Skeletal Muscle depends upon the release of Calcium from the Sarcoplasmic Reticulum to initiate the cross bridge cycle.

Select one of the following:

  • True
  • False

Explanation

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