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Lecture 23 Cardiac and Smooth Muscle

Daniel Mosele 10 questions

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  1. 1Which of the following is true of both Skeletal and Smooth Muscle
    1. APresence of the Neuromuscular Junction
    2. BPhosphorylation of Myosin during the Crossbridge Cycle
    3. CPresence of both Thick and Thin myofilaments
    4. DPresence of Troponin
    5. EPresence of Actin
    6. FAcetylcholine is involved
    7. GCalmodulin Complex
    8. HCrossbridge Cycle triggered by an increase in Intracellular Calcium
    9. IHormones are involved in the activation
    10. JNoradrenaline is invovled
  2. 2In Comparison to Skeletal Muscle, Cardiac Muscle cells:
    1. AHave Less Nuclei
    2. BHave More Nuclei
    3. CHave Longer Action Potentials
    4. DHave Shorter Action Potentials
    5. EInvolve Phosphorylation of Myosin, instead of altering the shape of troponin and position of tropomyosin to reveal a binding site
    6. FAre More branch-like
    7. GAre More linear
    8. HHave Intercalated Discs
    9. IDo not have Intercalacted Discs
    10. JContraction is triggered by the release of Intracellular Calcium, not extracellular Calcium
  3. 3[blank_start]A Pacemaker Cell[blank_end] in the Heart releases an Action Potential, these spread across the heart. [blank_start]Purkinje Fibres[blank_end] help enhance the spread of the action potential. When the action potential spreads across the cell membrane of individual cardiacmyocytes they invade [blank_start]T tubules[blank_end] (invaginations in the membrane). These cause the opening of [blank_start]Voltage Calcium Channels[blank_end]. [blank_start]Extracellular Calcium[blank_end] then moves into the cytosol. The presence of [blank_start]Calcium[blank_end] in the cytosol causes further release of [blank_start]calcium from the Sarcoplasmic Reticulum[blank_end]. This phenomenon is termed [blank_start]Calcium Dependent Calcium Release[blank_end]. This results in [blank_start]Systole[blank_end]. Strength/Force of Contraction can be modulated by the concentration of [blank_start]Extracellular Calcium.[blank_end]
    1. APacemaker Cells
    2. BPurkinje Fibres
    3. CSympathetic Nerves
    4. DAlpha Motor Neurons
    5. ECardiomyocytes
    6. FPurkinje Fibres
    7. GPacemaker Cells
    8. HCardiomyocytes
    9. ISympathetic Nerves
    10. JAdrenaline
    11. KExtracellular Calcium
    12. LNoradrenaline
    13. MGAP Junctions
    14. NDesmosomes
    15. OT tubules
    16. PD Tubules
    17. QM Tubules
    18. RC Tubules
    19. SS Tubules
    20. TVoltage Gated Calcium Channels
    21. UVoltage Gated Sodium Channels
    22. VVoltage Gated Potassium Channels
    23. WVoltage Gated Chloride Channels
    24. XLigand Gated Calcium Channels
    25. YLigand Gated Chloride Channels
    26. ZLigand Gated Potassium Channels
    27. AALigand Gated Sodium Channels
    28. ABExtracellular Calcium
    29. ACExtracellular Sodium
    30. ADExtracellular Chloride
    31. AEExtracellular Potassium
    32. AFIntracellular Calcium
    33. AGIntracellular Sodium
    34. AHIntracellular Chloride
    35. AIIntracellular Potassium
    36. AJCalcium
    37. AKSodium
    38. ALATP
    39. AMPotassium
    40. ANChloride
    41. AOCalmodulin
    42. APAcetylcholine
    43. AQNoradrenaline
    44. ARCalcium from the Sarcoplasmic Reticulum
    45. ASCalcium from Vesicles
    46. ATCalcium from the Interstitial Space
    47. AUSodium from the Sarcoplasmic Reticulum
    48. AVSodium from Vesicles
    49. AWSodium from the Interstitial Space
    50. AXCalcium Dependent Chloride Release
    51. AYCalcium Dependent Sodium Release
    52. AZSodium Dependent Calcium Release
    53. BACalcium Dependent Calcium Release
    54. BBChloride Dependent Calcium Release
    55. BCSodium Dependant Potassium Release
    56. BDPotassium Dependant Calcium Release
    57. BESystole
    58. BFDiastole
    59. BGExtracellular Calcium.
    60. BHExtracellular Potassium
    61. BIExtracellular Chloride
    62. BJExtracellular Sodium
    63. BKIntracellular Calcium
    64. BLIntracellular Potassium
    65. BMIntracellular Chloride
    66. BNIntracellular Sodium
  4. 4With regards to the Transverse Region of Intercalated Discs, which of the following is false?
    1. AA: Align with the Z Line
    2. BB: Contain Desmosomes
    3. CC: Aid in Mechanical Cohesion
    4. DD: Rich in GAP Junctions
    5. EE: None of the Above
  5. 5In Smooth Muscle Myosin heads are present along the entire length of the thick filament
    1. ATrue
    2. BFalse
  6. 6Which of the following Statements regarding Smooth Muscle is correct?
    1. AT Tubules are present
    2. BSarcoplasmic Reticulum is rudimentary
    3. CCaveoli are present
    4. DActin filaments are attached to Dense Bodies
    5. EMyosin filaments are attached to Dense Bodies
    6. FDesmin forms a diagonal network across the cell membrane
    7. GWhen Myosin filaments contract they pul on Dense Bodies, and everything is pulled together
    8. HWhen Actin filaments contract they pull on Dense Bodies, and everything is pulled together
    9. IAll Smooth Muscle most be directly stimulated
    10. JGAP Junctions are present in all smooth muscle tissue
  7. 7Multi-unit Smooth Muscle has
    1. AFew GAP Junctions
    2. BMany GAP Junctions
    3. CPresent in the Large Airways of the Lungs
    4. DPresent in the Ciliary Muscle of the Eye
    5. EPresent in the Wall of the Uterus
    6. FPresent in the Wall of the Jejenum
    7. GMultiple adherence points (Desmosomes)
    8. HPoor response to Stretch
    9. IDiscrete points of Innervation
    10. JDirect stimulation only present in a few cells
  8. 8Single Unit Smooth Muscle contraction can be innervated/affected by
    1. AHormones
    2. BNeural Input
    3. CpH
    4. DOxygen Levels
    5. EBody Temperature
    6. FAll of the Above
    7. GHormones and Neural Input Only
  9. 9ATP is essential in Smooth Muscle, but has a different role to that of Skeletal Muscle. ATP is required as a substrate for Myosin Light Chain Kinase in the phosphorylation of Myosin Cross Bridges.
    1. ATrue
    2. BFalse
  10. 10Smooth Muscle, like Skeletal Muscle depends upon the release of Calcium from the Sarcoplasmic Reticulum to initiate the cross bridge cycle.
    1. ATrue
    2. BFalse

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Description
DVM1 Veterinary Bioscience: Cells to Systems (Theme 7: Cell Communication - Electrical) Quiz on Lecture 23 Cardiac and Smooth Muscle, created by Daniel Mosele on 02/06/2016.
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