Mechanisms of Cell injury

Question 1 of 12

1

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Terminology:
1. : cause of disease
2. : the mechanism of how disease develops
3. : structural changes in tissues and organs
4. : functional consequences
5. : before death
6. : after death
7. : postmortem and tissue biopsy
8. : postmortem with naked eye
9. : postmortem with microscope
10. : analysis of body fluids and cells

Explanation

Question 2 of 12

1

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ATP depletion is caused by ( hypoxia, free radicals ) resulting in ( decreased, increased ) oxidative posphorylation, ( decreased, increased ) ATP, ( increased, decreased ) anaerobic glycolysis, ( decreased, increased ) glycogen and decreased pH. the sodium potassium pump fails and ribosomes ( detach from, attach to ) the RER.

Explanation

Question 3 of 12

1

the three main causes of membrane damage are:
1. ❌ that cause lipid peroxidation
2. ❌ from chemicals, viruses etc.
3. ❌ resulting in ATP depletion.

Drag and drop to complete the text.

free radicals

direct damage

Hypoxia

Explanation

Question 4 of 12

1

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the most reactive oxygen species are , and .

Explanation

Question 5 of 12

1

which of the following are sources of free radicals?

Select one or more of the following:

by-products of oxidative metabolism
phagocytic cells
metals
organophosphates
reperfusion following necrosis
reperfusion following ischaemia
radiation and UV light
drug and chemical exposure
nitric oxide.

Explanation

Question 6 of 12

1

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free radicals injure cells via:
1. leading to extensive membrane damage
2. which causes sing strand breaks
3. which causes the oxidation of amino acids

Explanation

Question 7 of 12

1

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two patterns of reversible cell injury include:
1. : acute cell swelling due to fluid influx
2. : cell swelling due to lipid accumulation

Explanation

Question 8 of 12

1

increased cytosolic calcium is associated with reversible cell injury.

Select one of the following:

True
False

Explanation

Question 9 of 12

1

what type of cell injury is seen here microscopically? is it reversible?

Select one or more of the following:

fatty change
hydropic degeneration
no it is not reversible
yes it is reversible

Explanation

Question 10 of 12

1

what type of cell injury is seen here grossly? is it reversible?

Select one or more of the following:

fatty change
hydropic degeneration
no it is not reversible
yes it is reversible

Explanation

Question 11 of 12

1

what type of cell injury is seen here microscopically? is it reversible?

Select one or more of the following:

fatty change
hydropic degeneration
no it is no reversible
yes it is reversible

Explanation

Question 12 of 12

1

what type of cell injury is seen here grossly? is it reversible?

Select one or more of the following:

fatty change
hydropic degeneration
yes it is reversible
no it is not reversible.

	Created by Kayleigh Van over 7 years ago

Pathology (Introductory principles) Quiz on Mechanisms of Cell injury, created by Kayleigh Van on 19/10/2016.

Mechanisms of Cell injury

Question 1 of 12

Fill the blank spaces to complete the text.

Explanation

Question 2 of 12

Select from the dropdown lists to complete the text.

Explanation

Question 3 of 12

the three main causes of membrane damage are: 1. ❌ that cause lipid peroxidation 2. ❌ from chemicals, viruses etc. 3. ❌ resulting in ATP depletion.

Drag and drop to complete the text.

Explanation

Question 4 of 12

Fill the blank spaces to complete the text.

the most reactive oxygen species are , and .

Explanation

Question 5 of 12

which of the following are sources of free radicals?

Select one or more of the following:

Explanation

Question 6 of 12

Fill the blank spaces to complete the text.

free radicals injure cells via: 1. leading to extensive membrane damage 2. which causes sing strand breaks 3. which causes the oxidation of amino acids

Explanation

Question 7 of 12

Fill the blank spaces to complete the text.

two patterns of reversible cell injury include: 1. : acute cell swelling due to fluid influx 2. : cell swelling due to lipid accumulation

Explanation

Question 8 of 12

increased cytosolic calcium is associated with reversible cell injury.

Select one of the following:

Explanation

Question 9 of 12

what type of cell injury is seen here microscopically? is it reversible?

Select one or more of the following:

Explanation

Question 10 of 12

what type of cell injury is seen here grossly? is it reversible?

Select one or more of the following:

Explanation

Question 11 of 12

what type of cell injury is seen here microscopically? is it reversible?

Select one or more of the following:

Explanation

Question 12 of 12

what type of cell injury is seen here grossly? is it reversible?

Select one or more of the following:

Explanation

the three main causes of membrane damage are:
1. ❌ that cause lipid peroxidation
2. ❌ from chemicals, viruses etc.
3. ❌ resulting in ATP depletion.

free radicals injure cells via:
1. leading to extensive membrane damage
2. which causes sing strand breaks
3. which causes the oxidation of amino acids

two patterns of reversible cell injury include:
1. : acute cell swelling due to fluid influx
2. : cell swelling due to lipid accumulation