6716313
Description
Quiz by Kayleigh Van , updated more than 1 year ago
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Created by Kayleigh Van
over 7 years ago
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Question 1
Question
Terminology:
1. [blank_start]aetiology[blank_end]: cause of disease
2. [blank_start]pathogenesis[blank_end]: the mechanism of how disease develops
3. [blank_start]morphological changes[blank_end]: structural changes in tissues and organs
4. [blank_start]clinical significance[blank_end]: functional consequences
5. [blank_start]antemortem[blank_end]: before death
6. [blank_start]postmortem[blank_end]: after death
7. [blank_start]anatomical pathology[blank_end]: postmortem and tissue biopsy
8. [blank_start]gross pathology[blank_end]: postmortem with naked eye
9. [blank_start]histopathology[blank_end]: postmortem with microscope
10. [blank_start]clinical pathology[blank_end]: analysis of body fluids and cells
Answer
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aetiology
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pathogenesis
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morphological changes
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clinical significance
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antemortem
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postmortem
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anatomical pathology
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gross pathology
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histopathology
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clinical pathology
Question 2
Question
ATP depletion is caused by [blank_start]hypoxia[blank_end] resulting in [blank_start]decreased[blank_end] oxidative posphorylation, [blank_start]decreased[blank_end] ATP, [blank_start]increased[blank_end] anaerobic glycolysis, [blank_start]decreased[blank_end] glycogen and decreased pH. the sodium potassium pump fails and ribosomes [blank_start]detach from[blank_end] the RER.
Answer
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hypoxia
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free radicals
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decreased
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increased
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decreased
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increased
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increased
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decreased
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decreased
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increased
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detach from
-
attach to
Question 3
Question
the three main causes of membrane damage are:
1. [blank_start]free radicals[blank_end] that cause lipid peroxidation
2. [blank_start]direct damage[blank_end] from chemicals, viruses etc.
3. [blank_start]Hypoxia[blank_end] resulting in ATP depletion.
Answer
-
free radicals
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direct damage
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Hypoxia
Question 4
Question
the most reactive oxygen species are [blank_start]superoxide[blank_end], [blank_start]hydrogen peroxide[blank_end] and [blank_start]hydroxyl radical[blank_end].
Answer
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superoxide
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hydrogen peroxide
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hydroxyl radical
Question 5
Question
which of the following are sources of free radicals?
Answer
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by-products of oxidative metabolism
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phagocytic cells
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metals
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organophosphates
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reperfusion following necrosis
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reperfusion following ischaemia
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radiation and UV light
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drug and chemical exposure
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nitric oxide.
Question 6
Question
free radicals injure cells via:
1. [blank_start]lipid peroxidation[blank_end] leading to extensive membrane damage
2. [blank_start]DNA damage[blank_end] which causes sing strand breaks
3. [blank_start]protein damage[blank_end] which causes the oxidation of amino acids
Answer
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lipid peroxidation
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DNA damage
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protein damage
Question 7
Question
two patterns of reversible cell injury include:
1. [blank_start]hydropic degeneration[blank_end]: acute cell swelling due to fluid influx
2. [blank_start]fatty change[blank_end]: cell swelling due to lipid accumulation
Answer
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hydropic degeneration
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fatty change
Question 8
Question
increased cytosolic calcium is associated with reversible cell injury.
Answer
- True
- False
Question 9
Question
what type of cell injury is seen here microscopically? is it reversible?
Answer
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fatty change
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hydropic degeneration
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no it is not reversible
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yes it is reversible
Question 10
Question
what type of cell injury is seen here grossly? is it reversible?
Answer
-
fatty change
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hydropic degeneration
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no it is not reversible
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yes it is reversible
Question 11
Question
what type of cell injury is seen here microscopically? is it reversible?
Answer
-
fatty change
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hydropic degeneration
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no it is no reversible
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yes it is reversible
Question 12
Question
what type of cell injury is seen here grossly? is it reversible?
Answer
-
fatty change
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hydropic degeneration
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yes it is reversible
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no it is not reversible.
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