Question 1
Question
Which of the following is not an adverse effect of isoniazid
Question 2
Question
Which of the following anticancer drugs is an alkylating agent
Answer
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Chlorabucil
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Methotrexate
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5-FU
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Asparaginase
Question 3
Question
This anticancer drug is an enzyme preparation isolated for E. Coli that hydrolyzes circulation L-asparagine to aspartic acid and ammonia. AE include include hypersensitivity rxn s/a rash, fever, chills, urticaria and bronchospasm.
Answer
-
Asparaginase
-
Chlorabucil
-
Methotrexate
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5-fluorouracil
Question 4
Question
Mindy is a 45 y/o female who comes in to your office due to stinging and burning down below. When asked about her social history she says that she has recently been divorced and been loving the single life and hitting up single events and has had several new sexual adventures. Pt notes that since she is in menopause she hasn't really been using that much protection. On exam you note several tender vesicular lesions on her labia. Which of the following would be your choice for tx of this patient?
Answer
-
Acyclovir
-
Methotrexate
-
Amoxicillin
-
Penicillin G
Question 5
Question
Bob is a 72 y/o male who is brought into your clinic due to confusion. Pt's daughter says he has experienced these sx before when the had a UTI. Urinalysis confirms this diagnosis. Which of the following drugs is contra-indicated to treat this pt.
Answer
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Ciprofloxacin
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Cephalexin
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Cefazolin
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Co-trimoxazole
Question 6
Question
This drug acts by binding to peptidoglycan strand of cell wall and prevents further growth of the cell wall. It is not absorbed from the GI tract and is excreted unchanged via the kidneys. What is this drug?
Answer
-
Vancomycin
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Bacitracin
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Ampicillin
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Doxycycline
Question 7
Question
Which of the following is NOT a beta lactam?
Answer
-
Pipericillin
-
Cephalexin
-
Cluvanic acid
-
Polymixins
Question 8
Question
Which of the following antiretroviral drugs is not safe during pregnancy?
Answer
-
Tenofovir
-
Emtricitabine
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Efaviren
-
Raltegravir
Question 9
Question
Which anticancer drug is a/w vitamin A toxicity which can be a/w HA, fever, and dry skin?
Answer
-
Retinoic Acid
-
Asparaginase
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Chlorabucil
-
Cyclophosphamide
Question 10
Question
Which antifungal is indicated for onychomycoses tinea corporis and tinea cruris
Answer
-
Terbinafine
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Grisoulvin
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Imidazole
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Itraconazole
Question 11
Question
Which antifungal class inhibits the enzyme 14-alpha-demethylase?
Answer
-
Azole antifungals
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Echinocandins
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Fluoroquinolones
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Nystatin
Question 12
Question
This class of antiretroviral drugs act by binding to reverse transcriptase, inhibits DNA polymerase (do not resemble ACTG)?
Answer
-
Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs)
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Nucleoside and Nucleotide Reverse Transcriptase Inhibitors (NRTIs)
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Protease Inhibitors (PIs) (-navir)
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Integrase Inhibitors
Question 13
Question
Which of the following conditions put patients at risk of hemolysis when being treated w/ chloroquine for malaria?
Answer
-
G6PD
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Sickle Cell Anemia
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HTN
-
Lupus
Question 14
Question
This group of antibiotics acts by inhibiting bacterial DNA gyrase [DNA gyrase converts closed circular DNA into supercoiled configuration] preventing supercoiling and stops DNA replication
Answer
-
Fluoroquinolones
-
Sulfonamides
-
Trimethoprim
-
Riframpin
Question 15
Question
Red man syndrome, a possible AE effect of vancomycin, is d/t which of the following mechanisms?
Answer
-
Mast breakdown, leading to histamine release and subcutaneous vasodilation
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Subcutaneous thrombocytopenia due to abnormal production of clotting factors
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Psych disorder where patients will paint their skin red and think they are the devil.
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None of the answers are correct.