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Monogenic inheritance

Sara Bean

  • Homozygous genetic cross results in all offspring being heterozygous 
  • Heterozygous genetic cross results in mix of homozygous and heterzygous offspring
  • Codominance = when both alleles are dominant so both are expressed --> blood types A and B (heterozygous is AB) and snapdragon white and red flowers (heterozygous is pink)
  • Multiple genes = when characteristic has more than two alleles (blood type has A, B and O)
  • Sex chromosomes --> females have XX but males have XY
  • Sex linkage = Y chromosome considerably shorter and don't have all the same genes as X so sometimes whatever allele is on the X is expressed if dominant or recessive <-- characteristic is classed as sex linked
    • Colour blindness
    • Haemophilia (slow blood clotting due to absence of blood clotting factor) if male gets the recessive gene on the X they won't have the corresponding dominant one so will get haemophilia. Heterozygous females = carriers

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