13119854
Descripción
Test por Alannah McDonnell, actualizado hace más de 1 año
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Creado por Alannah McDonnell
hace alrededor de 6 años
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Pregunta 1
Pregunta
What is normal GFR in adult humans?
Respuesta
-
100-125 ml/min
-
4500-6000 ml/min
-
1 - 2 ml/min
-
540 - 900 ml / min
Pregunta 2
Pregunta
What does glomerular ultra-filtrate consist of?
Respuesta
-
water
-
small solutes
-
large solutes
-
plasma
-
urine
Pregunta 3
Pregunta
Glomerular Ultrafiltrate is normally ...
Respuesta
-
containing proteins
-
protein free
Pregunta 4
Pregunta
What does Regulated reabsorption of water and solutes allow for?
Respuesta
-
regulation of extracellular fluid volume
-
regulation of osmolality
-
regulation of acid base balance
-
homeostasis of whole body phosphate concentrations
-
homeostasis of whole body calcium concentrations
-
homeostasis of whole body potassium concentrations
Pregunta 5
Pregunta
Which of these are freely filtered but not reabsorbed?
Respuesta
-
urea
-
creatinine
-
water
-
salt
-
proteins
Pregunta 6
Pregunta
Permselectivity = the restriction of the [blank_start]permeation[blank_end] of [blank_start]macromolecules[blank_end] across [blank_start]the glomerular barrier[blank_end] on the basis of [blank_start]molecular[blank_end] size, charge, and physical [blank_start]configuration.[blank_end]
Respuesta
-
permeation
-
permeability
-
macromolecules
-
micromolecules
-
the glomerular barrier
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bowmans space
-
molecular
-
atomic
-
configuration.
-
conglobulation.
Pregunta 7
Pregunta
Podocytes = [blank_start]specialized[blank_end], highly [blank_start]differentiated[blank_end] cells which line the [blank_start]outside[blank_end] of glomerular [blank_start]capillaries[blank_end] and thus face the [blank_start]Bowman's space[blank_end] and the primary [blank_start]urine[blank_end]
Respuesta
-
specialized
-
common
-
differentiated
-
similar
-
outside
-
inside
-
capillaries
-
vessels
-
Bowman's space
-
glomerulus
-
urine
-
urea
Pregunta 8
Pregunta
Podocytes have a ____ cell body
Respuesta
-
large
-
small
-
average sized
Pregunta 9
Pregunta
The diaphragm in the podocyte covers the...
Respuesta
-
filtration slit
-
fenestration
-
foot process
-
whole cell body
Pregunta 10
Pregunta
What type of collagen composes the backbone of the fibrous network in the glomerular basement membrane?
Respuesta
-
type 1 collagen
-
type 2 collagen
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type 3 collagen
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type 4 collagen
Pregunta 11
Pregunta
What is the normal urine flow rate in adult humans?
Respuesta
-
1 - 2 ml/min
-
100-125ml/min
-
540-900 ml/min
-
900-1500ml/min
Pregunta 12
Pregunta
What is the normal renal blood flow rate in adult humans?
Respuesta
-
900-1500 ml/min
-
4500 - 6000 ml/min
-
540-900 ml/min
-
1-2 ml/min
Pregunta 13
Pregunta
What is the normal renal plasma flow rate in adult humans?
Respuesta
-
540-900 ml/min
-
4500-6000 ml/min
-
900 - 1500 ml/min
-
1-2ml/min
Pregunta 14
Pregunta
what does the filtration fraction generally measure?
Respuesta
-
20-25%
-
40-45%
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50-60%
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80-85%
Pregunta 15
Pregunta
Roughly how much primary urine is produced per day?
Respuesta
-
140L
-
200L
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140ml
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500L
-
10L
Pregunta 16
Pregunta
Roughly how much filtered fluid is reabsorbed?
Respuesta
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99%
-
1%
-
20%
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50%
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75%
Pregunta 17
Pregunta
Drag and drop the right answer. all answers match up with a space, there are none spare.
For the 0 options, the 00 is in the % column and the normal 0 is in the urine column)
Respuesta
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17
-
0.63
-
0.5
-
12.9
-
125
-
33
-
1.4
-
0.128
-
0.06
-
0.0048
-
0.134
-
0
-
18
-
1.8
-
0.72
-
9.5
-
0.96
-
1
-
00
-
55
-
130
Pregunta 18
Respuesta
-
Proximal convoluted tubule
-
glomerulus
-
Glomerular capsule
-
efferent arteriole
-
blood flow
-
afferent arteriole
-
glomerular filtrate
-
fenestrae
-
podocyte
-
capillary endothelium
Pregunta 19
Pregunta
Glomerular capillaries are __________
Respuesta
-
fenestrated
-
continuous
Pregunta 20
Pregunta
Endothelial cells _______ determine the permselectivity of the glomerular barrier.
Respuesta
-
do
-
do not
Pregunta 21
Pregunta
The endothelial cell coat has _________
Respuesta
-
charge-selective properties
-
no charge-selective properties.
-
size selective properties
-
molecular weight selective properties
Pregunta 22
Pregunta
___________ density of fenestrae facilitates ___________ permeability
Respuesta
-
high, high
-
low, low
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high, low
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low, high
Pregunta 23
Pregunta
Which of these are important components that contribute to the selective properties of the glomerular basement membrane barrier?
Respuesta
-
ptoteoglycans such as agrin
-
ptoteoglycans such as perlecan
-
glycoproteins
Pregunta 24
Pregunta
Where is the endothelial cell surface layer?
Respuesta
-
on the luminal side of the blood vessels
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on the fenestrated side of the blood vessels
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on the outside of the blood vessels
-
within the glomerulus
Pregunta 25
Pregunta
What are the 2 components of the endothelial cell surface layer?
Respuesta
-
the glycocalyx
-
the endothelial cell coat
-
the endometrial cell jacket
-
the caloglycax
-
the glucose layer
Pregunta 26
Pregunta
Thye glycocalyx is the...
Respuesta
-
plasma-membrane-bound part of the layer
-
the more loosely associated part of the layer
Pregunta 27
Pregunta
Thye endothelial cell coat is the...
Respuesta
-
more loosely associated part of the layer
-
plasma-membrane-bound part of the layer
Pregunta 28
Pregunta
*** The endothelial cell surface layer is composed of....
Respuesta
-
negatively charged glycoproteins
-
glycosaminoglycans
-
membrane associated and secreted proteoglycans
Pregunta 29
Pregunta
drag and drop the substances along the graph in relation to where there relative permeability lies
Respuesta
-
H2O
-
NaCl
-
Glucose
-
Inulin
-
Myoglobin
-
Hemoglobin
-
Albumin
Pregunta 30
Pregunta
Filtration of solutes that are not reabsorbed serves as an ineffective mechanism for their excretion
Respuesta
- True
- False
Pregunta 31
Pregunta
Which of these about polo trees are true?
Respuesta
-
Have long extending cytoplasmic foot processes
-
Foot processes are separated by a filtration slit
-
The filtration slit is 25-60nm wide
-
The filtration slit is covered by a diaphragm
-
One of the proteins that make up the diaphragm is nephrin
-
Nephrin is very safe
Pregunta 32
Pregunta
When mutated, nephrin...
Respuesta
-
Causes massive leakage of protein
-
Causes severe consequences for patients with congenital nephrotic syndrome.
-
Causes the diaphragm in the kidney to close
-
Causes excess water to be absorbed
-
Causes alcoholism
Pregunta 33
Pregunta
The basement membrane allows free passage of neutral molecules up to...
Respuesta
-
6Kd MW (18A radius)
-
16Kd MW (8A radius)
-
12Kd MW (24A radius)
-
2A MW (7Kd radius)
Pregunta 34
Pregunta
Negatively charged pores restrict passage of .... molecules
Respuesta
-
Large
-
Small
-
Medium
-
Long
-
Short
Pregunta 35
Pregunta
In disease states, protein Irial may be due to loss of negatively charge selectivity or to increasing numbers of large size pores
Respuesta
- True
- False
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