Test
DF15 Tablet coating
Este test tiene tipos de pregunta que se abren en el reproductor de siempre.
Preguntas del test (5)
1There are 6 main reasons why we coat tablets.
1. Protect tablet ingredients
From [blank_start]moisture[blank_end], pH ranges, during [blank_start]transportation[blank_end], storage, etc.
2. Mask taste of bitter drugs
e.g. steroids are [blank_start]bitter[blank_end], polyphenols are astringent, lipids are [blank_start]bland[blank_end]. Improving taste improves patient [blank_start]compliance[blank_end]. Done via film coating with [blank_start]sweeteners or polymers[blank_end].
3. Identification of tablets
By [blank_start]embossing[blank_end]/scoring or using [blank_start]edible[blank_end] inks/dyes. Provides identification [blank_start]outside[blank_end] of packaging, protects from [blank_start]counterfeiting[blank_end], provides [blank_start]distinction[blank_end] from competition brands.
4. Improving the ease of swallowing
Difficulty swallowing, dysphagia, may be because of [blank_start]dry[blank_end] mouth caused by other condition, [blank_start]Parkinson's, Alzheimer's, stroke[blank_end], or lack of [blank_start]coordination[blank_end]. Smooth small tablets are easier to administer.
5. Easier [blank_start]handling[blank_end] during manufacture
6. Functional coating to give enteric coating / [blank_start]controlled release[blank_end] properties- Amoisture
- Btransportation
- Cbitter
- Dbland
- Ecompliance
- Fsweeteners or polymers
- Gembossing
- Hedible
- Ioutside
- Jcounterfeiting
- Kdistinction
- Ldry
- MParkinson's, Alzheimer's, stroke
- Ncoordination
- Ohandling
- Pcontrolled release
2There are 3 main types of coating.
1. FIlm coating
- most [blank_start]popular[blank_end]
- spray [blank_start]liquid polymer[blank_end] onto surface
- [blank_start]2-3%[blank_end] increase in weight
- [blank_start]single stage[blank_end] process
- [blank_start]1-2[blank_end]h process, organic solvents used for quick drying
- can modify for controlled release
2. Sugar coating
- successive application of [blank_start]sucrose[blank_end] solutions with [blank_start]colour and waxes[blank_end] for shine
- [blank_start]30-50%[blank_end] increase in tablet weight
- [blank_start]multi-stage[blank_end] process
- [blank_start]8[blank_end]h+ process
- only [blank_start]enteric[blank_end] controlled release product possible
- [blank_start]printing[blank_end] possible
3. Compression coating
- based on pre-formulated tablet core
- [blank_start]separates[blank_end] incompatible materials
- can make modified release products
- [blank_start]dry[blank_end] process- Apopular
- Bliquid polymer
- C2-3%
- Dsingle stage
- E1-2
- Fsucrose
- Gcolour and waxes
- H30-50%
- Imulti-stage
- J8
- Kenteric
- Lprinting
- Mseparates
- Ndry
3Select all the tablets it would be unsafe for a patient to cut or crush.
- ASugar coated
- BEnteric coated
- CFunctional coated
4Multiparticulates are pellets, granules, beads or spheroids which are [blank_start]150[blank_end]micrometres to [blank_start]2-3[blank_end]mm in size. They are often [blank_start]coated[blank_end] and can be [blank_start]single or multiple[blank_end] drug formations. They are incorporated into a single dosage unit of a [blank_start]hard gel[blank_end] capsule, [blank_start]compressed[blank_end] tablet, or [blank_start]sachet[blank_end].
The advantages of multiparticulate drug delivery systems are the [blank_start]flexibility[blank_end] of form of the final product, the stable [blank_start]shelf life[blank_end], the ability to have different coatings for different [blank_start]release profiles[blank_end], the reduced dose variation due to uniform [blank_start]gastric emptying[blank_end], and that they're able to be [blank_start]mixed with food[blank_end] for easier swallowing.- A150
- B100
- C2-3
- D5-10
- Ecoated
- Fsingle or multiple
- Ghard gel
- Hcompressed
- Isachet
- Jflexibility
- Kshelf life
- Lrelease profiles
- Mgastric emptying
- Nmixed with food
5Fixed dose combinations are the delivery of [blank_start]2 or more[blank_end] drugs in a single dose form. This improves [blank_start]patient adherence[blank_end] by reducing [blank_start]the pill burden[blank_end] and ordering of medications is [blank_start]simplified[blank_end].
- A2 or more
- Bpatient adherence
- Cthe pill burden
- Dsimplified
Información
- Descripción
- (Formulation) PHCY211 Test sobre DF15 Tablet coating, creado por Mer Scott el 30/04/2018.
- Autor
- Mer Scott
- Idioma
- English
- Visitas
- 11
- Historial
- Creado el 30 abr 2018 · actualizado el 30 abr 2018
- Etiquetas
- Valoración
- Aún sin valoraciones Valora este test