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MD1 - 2 Drug Stability

Mer Scott 11 preguntas

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Preguntas del test (11)

  1. 1How much drug degradation is acceptable a) typically in pharmacopoeia specifications b) in calculations for this course?
    1. Aa) 1-2% b) 10%
    2. Ba) 0.5-1% b) 5%
    3. Ca) 5-10% b) 15%
  2. 2Label the conc. vs time graphs.Imagen de la pregunta 2
    1. A1st order
    2. B0 order
  3. 32nd order rate constant units are time^-1.conc^-1 so [blank_start]s^-1 * M^-1[blank_end].
    1st or apparent 1st order rate constant units are time^-1 so [blank_start]s^-1[blank_end].
    0 order rate constant units are conc.time^-1 so [blank_start]M * s^-1[blank_end].
    1. As^-1 * M^-1
    2. Bs^-1
    3. CM * s^-1
  4. 4Select the correct equation for 0 order reactions.
    1. A[D] = [D]o - k(obs) * t
    2. Bln[D] = ln[D]o - k(obs) * t
    3. C[D] = [D]o * e^(k(obs) * t)
  5. 5Which equation would you use to find the half life of a 1st order reaction?
    1. At0.5 = 0.693 / k(obs)
    2. Bt0.5 = 0.105 / k(obs)
    3. Ct0.5 = 0.693 * [D]o / k(obs)
    4. Dt0.5 = 0.5 * [D]o / k(obs)
  6. 6Which equation would you use to find the shelf life of a drug with 1st order reaction?
    1. At0.9 = 0.105 / k(obs)
    2. Bt0.9 = 0.683 / k(obs)
    3. Ct0.9 = [D]o * 0.9 / k(obs)
    4. Dt0.9 = [D]o * 0.1 / k(obs)
  7. 7Which equation would you use to find the half life of a drug with a 0 order reaction?
    1. At0.5 = [D]o * 0.5 / k(obs)
    2. Bt0.5 = [D]o * 0.1 / k(obs)
    3. Ct0.5 = [D] * 0.5 / k(obs)
    4. Dt0.5 = [D] * 0.1 / k(obs)
  8. 8Which equation would you use to find the shelf life of a drug with a 0 order reaction?
    1. At0.9 = [D]o * 0.1 / k(obs)
    2. Bt0.9 = [D]o * 0.9 / k(obs)
    3. Ct0.9 = [D]o * 0.5 / k(obs)
  9. 9Apparent 1st order reactions describe a situation where one of the reactants is present in large excess or does not effect the overall reaction.
    1. AVerdadero
    2. BFalso
  10. 10t0.9 (0 order) is independent of concentration, while t0.5 (1st order) depends on the initial drug concentration.
    1. AVerdadero
    2. BFalso

Información

Descripción
(Medicines) PHCY211 Test sobre MD1 - 2 Drug Stability, creado por Mer Scott el 10/05/2018.
Idioma
English
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