Test
Pharmacology Vet 202 Chapter Ten Study Guide
Preguntas del test (25)
1There are three main considerations that must be made when deciding if an antimicrobial will be a successful choice to control a pathogenic infection. These include all of the following except
- Athe animal must tolerate high drug concentrations.
- Bthe antimicrobial must reach the site of infection at appropriate concentrations.
- Cthe antimicrobial must not cause any adverse effects.
- Dthe microbe must be susceptible to the medication.
2A dog is being treated for a Staphylococcal infection with an antibiotic that has a MTD that is lower than the laboratory-determined MIC for this drug-pathogen relationship. Should this antimicrobial be used?
- ANO
- BYES
- CMAYBE
- Dcannot be determined with this limited information
3Which of the following organizations is the division of the Centers for Disease Control and Prevention that is responsible for tracking how bacterial resistance and sensitivity profiles change over time?
- AAPHIS
- BUSGS
- CWHO
- DNARMS
4A strain of E. coli has been exposed to low levels of an antibiotic. The small number of remaining bacteria after this treatment results in a pathogen population that is more resistant to the antibiotic than prior to the treatment. As these bacteria replicate, they pass this resistance profile to their daughter cells. This type of antibiotic resistance transmission is considered
- Ahorizontal transfer.
- Bvertical transfer.
- Cspontaneous resistance.
- Dtransposon mediated transfer
5It is important to understand the potential for drug residues when choosing therapies for specific groups of animals. For which of the following animals would drug withdrawal times need to be known?
- Astandardbred horses.
- Bservice dogs.
- Calpacas raised for their hair.
- Dlaying hens.
- Eshelter cats.
6It is not recommended to treat animals with bacteriostatic drugs such as tetracyclines while simultaneously treating with bacteriocidal drugs such as penicillin. Why?
- APenicillin only kills active growing bacteria
- BTetracyclines form toxic compounds when exposed to penicillin
- CToo many bacteria are killed with this combo therapy
- DTetracycline use results in beta-lactam resistance
7A bacterial strain was tested at the state veterinary diagnostic laboratory and was shown to be resistant to amoxicillin. Of the following, which would be the best choice to use for treating an infection with this bacterial strain?
- APenicillin
- BClavamox
- CCeftiofur
- DAmpicillin
- EEnrofloxacin
8Sulfonamides are very wide spectrum antimicrobials that work via disruption of microbial folic acid synthesis. Which of the following statements regarding sulfonamides is not true?
- ASulfonamides are antimicrobials that have been used for many years
- BSulfonamides are bacteriocidal drugs unless potentiated
- CSulfonamides are effective against protozoal diseases
- DSome sulfonamides function as anti-inflammatories
- ESulfonamides are becoming increasingly less effective because of bacterial resistance
9Which of the following drug-adverse effect pairs is incorrect?
- APenicillin–hypersensitivity
- BSulfonamides–dry eye
- CChloramphenicol–elevated red blood cell production
- DTetracycline–tooth discoloration
- ETilmicosin–cardiotoxicity
10What drugs, in addition to anti-inflammatories such as glucocorticoids and antibiotics such as the aminoglycosides, are often included in otic preparations for external ear infections in companion animals?
- AOsmotic agents such as mannitol
- BAntifungal drugs such as clotrimazole
- CAntiviral drugs such as interferon
- DBacteriostatic drugs such as florphenicol
11The lowest concentration of a drug needed to inhibit bacterial growth is called:
- Aminimum incremental concentration.
- Bminimum interfering concentration.
- Cminimum inhibitory concentration.
- Dminimum inhibitory chemical.
12If a drug’s MIC is > MTD
- AThe bacteria are considered to be susceptible to the drug
- BThe drug concentration needed to inhibit the pathogen will not be safe
- CThe drug will not be well tolerated
- DThe drug will only inhibit the bacterial cycle
13It has been shown that there is a strong correlation between antibiotic use in food animals and
- ANARMS has been established by the CDC to monitor levels.
- Bantimicrobial resistance.
- Czoonotic bacterial have been introduce.
- DAll of the above
14When bacteria make physical contact with another bacterium and transfer a plasmid this is called
- Abinary fission.
- Bhorizontal transmission.
- Cvertical transmission.
- Dantibiotic resistance.
15Residue of a drug that can be found in a food product can be dangerous because
- Ait can lead to selection for resistant bacteria in the intestinal tract of humans.
- Bit can cause allergic reactions in the humans that consume or handle it.
- CA and B
- DNone of the above are true
16Drugs that target cell wall synthesis are most active against the bacteria’s.
- ADivision phase
- BResting phase
- CSpore phase
- DHyphal phase
17All of the following are penicillins except
- Aamoxicillin.
- Bampicillin.
- Ccloxacillin.
- Dgentocillin.
18Beta-lactams can be a good choice for urinary tract infections because
- Athey are inactivated in urine.
- Bthey are heavily metabolized in the liver.
- Cthey pass unmetabolized by passive diffusion across the glomerulus.
- Dthey are metabolized by the kidney.
19The addition of ____________ and benzathine to penicillin G delays absorption from IM or SC routes.
- Aprocaine
- BK+
- CNa+
- Daqueous
20Tetracyclines are
- Abacteriostatic.
- Bbacteriocidal.
- CThe same as sulfonamides.
- Dhydrophobic.
21Which of the following are not considered primary targets for antimicrobial therapies?
- ARibosomal protein production
- BNucleic acid replication factors
- CNucleic acid transcription factors
- DCell membrane
- ECell wall
22Which of these medications is the odd drug?
- AGentamicin
- BTulathromycin
- CStreptomycin
- DKanamycin
- EAmikacin
23Why isn’t gentamicin used to treat bacterial enteritis localized in the colon?
- ABecause no infectious agents are located in the colon
- BBecause the colon is very anaerobic
- CMost enteric diseases aren’t bacterial but instead viral
- DGentamicin destroys cell membranes, which worsens the enteritis
- EGentamicin is not a very effective antibiotic for any disease
24Antibiotics such as kanamycin that function by reaching a relatively high serum level are considered ___________-dependent drugs, while those that need to be in the body continuously are considered ____________-dependent drugs.
- Aserum, tissue
- Bbacterial, viral
- Ctemperature, pressure
- Dconcentration, time
25A urinary tract infection (UTI) was cultured in the regional veterinary diagnostic laboratory, and MICs were computed based on serial dilution assay. Penicillin had an MIC double the referenced dosage that can be accomplished in the serum. Regardless, the clinician still decided to use penicillin to treat this infection. Why?
- APenicillins reach high levels in the urine
- BPenicillin is cheap
- CPenicillin is the only drug labelled for treatment of UTI
- DAll other drugs are excreted through the bile
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- Test sobre Pharmacology Vet 202 Chapter Ten Study Guide, creado por Kelly Kinsinger el 30/10/2018.
- Autor
- Kelly Kinsinger
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- English
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