17526516
Descripción
Test por Matthew Coulson, actualizado hace más de 1 año
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Creado por Matthew Coulson
hace alrededor de 5 años
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Pregunta 1
Pregunta
Endometrial polyps are a common cause of dysfunctional uterine bleeding and typically occur in [blank_start]post-menopausal[blank_end] women.
Respuesta
-
post-menopausal
-
pre-pubertal
-
pre-menopausal
Pregunta 2
Pregunta
The peak incidence of endometrial carcinoma is [blank_start]50-60 years[blank_end].
It is uncommon for endometrial carcinoma to present in those [blank_start]under 40[blank_end]
Respuesta
-
under 40
-
over 65
-
50-60 years
-
30-40 years
-
70-80 years
Pregunta 3
Pregunta
Hereditary Non-Polyposis Colorectal Cancer (HNPCC) is a hereditary malignant syndrome which leaves the individual highly susceptible to other forms of cancer.
HNPCC is also known as [blank_start]Lynch[blank_end] Syndrome
Respuesta
-
Lynch
Pregunta 4
Pregunta
Lynch Syndrome, as well as predisposing the individual to colorectal cancer (HNPCC), also leaves the individual at high risk of which three of the following cancers?
Respuesta
-
Endometrial cancer
-
Breast cancer
-
Ovarian cancer
-
Vulval cancer
-
Lung cancer
-
Oesophageal cancer
Pregunta 5
Pregunta
Which two of the following are Type I Endometrial Carcinomas?
Respuesta
-
Endometrioid
-
Serous
-
Clear Cell
-
Mucinous
Pregunta 6
Pregunta
Which two of the following are Type II Endometrial Carcinomas?
Respuesta
-
Endometrioid
-
Mucinous
-
Serous
-
Clear Cell
Pregunta 7
Pregunta
[blank_start]Type I[blank_end] Endometrial Carcinomas are associated with unopposed Oestrogen and atypical hyperplasia
[blank_start]Type II[blank_end] Endometrial Carcinomas are associated with TP53 mutation
Respuesta
-
Type II
-
Type I
Pregunta 8
Pregunta
A serous endometrial carcinoma is associated with unopposed oestrogen
Respuesta
- True
- False
Pregunta 9
Pregunta
Atypical hyperplasia is a precursor to clear cell endometrial carcinoma
Respuesta
- True
- False
Pregunta 10
Pregunta
The precursor to endometrioid carcinoma is atypical hyperplasia.
Respuesta
- True
- False
Pregunta 11
Pregunta
Mucinous Endometrial Carcinomas are associated with TP53 mutation
Respuesta
- True
- False
Pregunta 12
Pregunta
Mucinous Endometrial Carcinomas are associated with unopposed oestrogen.
Respuesta
- True
- False
Pregunta 13
Pregunta
Which of the following are associated with Microsatellite Instability?
Respuesta
-
Endometrioid Endometrial Carcinoma
-
Mucinous Endometrial Carcinoma
-
Serous Endometrial Carcinoma
-
Clear Cell Endometrial Carcinoma
Pregunta 14
Pregunta
Which condition is defined as the following?
"Germline mutation of DNA mismatch repair genes"
[blank_start]Lynch Syndrome[blank_end]
Respuesta
-
Lynch Syndrome
Pregunta 15
Pregunta
Obesity is a highly substantial risk factor for endometrial carcinoma
Respuesta
- True
- False
Pregunta 16
Pregunta
Obesity is a risk factor for endometrial carcinoma as fat cells called adipocytes express an enzyme called [blank_start]aromatase[blank_end] which converts ovarian androgens into oestrogens, thus promoting endometrial proliferation.
Respuesta
-
aromatase
Pregunta 17
Pregunta
Lynch Syndrome has an autosomal [blank_start]dominant[blank_end] inheritance pattern
Respuesta
-
dominant
Pregunta 18
Pregunta
One of the characteristic traits of Lynch Syndrome is a lack of Microsatellite Instability
Respuesta
- True
- False
Pregunta 19
Pregunta
Type II Endometrial Carcinomas (Serous and Clear Cell) are more aggressive than Type I cancers as they spread along the fallopian tube mucosa allowing extrauterine presentation.
Respuesta
- True
- False
Pregunta 20
Pregunta
Which of the following Type II Endometrial Carcinomas is known to spread to the peritoneum early in the disease process?
Respuesta
-
Serous Endometrial Carcinoma
-
Clear Cell Endometrial Carcinoma
Pregunta 21
Pregunta
Endometrioid carcinoma has good prognosis as it is usually confined to the uterus at presentation
Respuesta
- True
- False
Pregunta 22
Pregunta
Uterine Leiomyomas are also called Uterine [blank_start]Fibroids[blank_end]
Respuesta
-
Fibroids
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