Growth Factors

Descripción

(Basics) Structural Basis for Biological Function Test sobre Growth Factors, creado por gina_evans0312 el 04/11/2013.
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Test por gina_evans0312, actualizado hace más de 1 año
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Creado por gina_evans0312 hace más de 10 años
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Resumen del Recurso

Pregunta 1

Pregunta
Epidermal Growth Factors are 53aa long, with an Mr of 40,000
Respuesta
  • True
  • False

Pregunta 2

Pregunta
What happens when you increase ornithine carboxylase and polyamine concentrations?
Respuesta
  • Cell division increases
  • Cell division decreases

Pregunta 3

Pregunta
In general effects ( inc glucose/aa transport and inc Na/K ATPase activity) what hormone are growth factors most like?
Respuesta
  • Insulin
  • Glucagon
  • Vasopressin
  • NO

Pregunta 4

Pregunta
Increase Na+/H+ pump activity causes what?
Respuesta
  • Alkylysation of the cytoplasm
  • Inc. DNA synthesis/mitosis
  • Inc protein production

Pregunta 5

Pregunta
How is tyrosine kinase kept inactive when a ligand is not bound?
Respuesta
  • The activation lip hides the active site
  • The active site is phosphorylated and inactive
  • A pseudosubstrate is bound

Pregunta 6

Pregunta
What form does inactive tyrosine kinase stay in?
Respuesta
  • Monomer
  • Dimer
  • Multimeric group

Pregunta 7

Pregunta
What effect does ligand binding have to tyrosine kinase?
Respuesta
  • Partial activation
  • Dimerisation
  • Monomerisation
  • Full activation

Pregunta 8

Pregunta
Once the activation lip is phosphorylated, what happens?
Respuesta
  • Phosphorylation continues of tyrosine kinase
  • Becomes fully active
  • Becomes partially active
  • Proteins bind to phosphorylated areas

Pregunta 9

Pregunta
Which of the following binds to phosphorylated tyrosine kinase?
Respuesta
  • GRB2
  • RAs
  • GEF
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