454649
Descripción
Test por gina_evans0312, actualizado hace más de 1 año
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Creado por gina_evans0312
hace más de 10 años
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Pregunta 1
Pregunta
What does genetic mapping rely on?
Respuesta
-
Inheritence phenotypes
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Polymorphic Markers
Pregunta 2
Pregunta
How is the tracing of inheritence phenotypes done?
Respuesta
-
Genetic markers i.e. SNP's
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Allele complimentation
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Meiotic Tests
Pregunta 3
Pregunta
1cM =
Respuesta
-
1% recombination
-
10% recombination
-
1kB
-
10kB
Pregunta 4
Pregunta
How are physical maps made?
Respuesta
-
Design markers that overlap along the genome
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Orientation of homologous chromosomes
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Allele studies
Pregunta 5
Pregunta
Physical maps must be made of physically isolated parts of the genome
Respuesta
- True
- False
Pregunta 6
Pregunta
A genetic marker acts as a reference point in a linkage study
Respuesta
- True
- False
Pregunta 7
Pregunta
Genes are usually used as markers in non-human studies. Why can they not be used in humans?
Respuesta
-
Human genes are more unstable
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Human genes vary too much
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Human genes are more highly conserved
Pregunta 8
Pregunta
What is the preferred form of marker in humans?
Respuesta
-
Polymorphic introns
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Polymorphic Exons
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SNP's
Pregunta 9
Pregunta
More polymorphic DNA= less useful
Respuesta
- True
- False
Pregunta 10
Pregunta
Homozygotes are more useful in genetic mapping than heterozygotes
Respuesta
- True
- False
Pregunta 11
Pregunta
How must markers be placed along the chromosome?
Respuesta
-
Evenly spaced
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As lightly as possibly
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As densely as possible
Pregunta 12
Pregunta
The aim it to combine genetic and physical maps
Respuesta
- True
- False
Pregunta 13
Pregunta
Once you have a marker with a high linkage to a disease/trait, how do you use the physical map?
Respuesta
-
Find the marker and look for genes very close to it
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Find the suspect gene and look for markers very close to it
-
Find the marker and look for genes as far away as possible
Pregunta 14
Pregunta
Which of the following are evenly distributed?
Respuesta
-
SNP's
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Minisatellites
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Microsatellites
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RFLP's
Pregunta 15
Pregunta
Microsatellites are highly polymorphic
Respuesta
- True
- False
Pregunta 16
Pregunta
Which of the following are most useful as markers?
Respuesta
-
RFLP's
-
Minisatellites
-
Microsetellites
-
SNP's
Pregunta 17
Pregunta
There are two alleles (usually) for RFLP's
Respuesta
- True
- False
Pregunta 18
Pregunta
How are minisatellites typed?
Respuesta
-
Southern Hybridisation
-
Gel Electrophoresis
-
PCR
Pregunta 19
Pregunta
There are more than 10^10 SNP's in the human genome
Respuesta
- True
- False
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