Macrocytic Anaemia

Descripción

(Red Blood Cells) Haematology and Anatomy Test sobre Macrocytic Anaemia, creado por gina_evans0312 el 08/01/2014.
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Resumen del Recurso

Pregunta 1

Pregunta
What defines Non-Megaloblastic Anaemia?
Respuesta
  • No large nucleus & excess cell membrane- no DNA involvement
  • Large nucleus, effected DNA

Pregunta 2

Pregunta
In Melagoblasic Anaemia, other blood cells are likely to be affected
Respuesta
  • True
  • False

Pregunta 3

Pregunta
Liver disease and alcohol cause what type of anaemia?p
Respuesta
  • Melagoblastic Macrocytic
  • Non-Megaloblastic Macrocytic

Pregunta 4

Pregunta
Which of the following is not a cause of Melagoblastic Anaemia?
Respuesta
  • HIV treatment
  • B12 deficiency
  • Iron deficiency
  • Folate deficiency

Pregunta 5

Pregunta
Pancytopaenia- a reduction of all three blood components
Respuesta
  • True
  • False

Pregunta 6

Pregunta
Why is pancytopaenia a symptom of Megaloblastic anaemia?
Respuesta
  • Cells apoptose due to DNA synthesis failure
  • Cells cannot be produced due to crowded bone marrow
  • Cells die because of insufficient folate

Pregunta 7

Pregunta
Megaloblastic anaemia leads to a shorter cell lifespan
Respuesta
  • True
  • False

Pregunta 8

Pregunta
Megaloblastic anaemia has an Inc MCV but Dec RDW
Respuesta
  • True
  • False

Pregunta 9

Pregunta
Erythrocyte precursors with retarded nuclear maturation
Respuesta
  • Megaloblasts
  • Oval Macrocytes
  • RBC fragments

Pregunta 10

Pregunta
Oval macrocytes -> larger reiculocytes ->
Respuesta
  • Larger R.B.C's
  • Smaller R.B.C's
  • Fragmented R.B.C's

Pregunta 11

Pregunta
In M.M.A, cells are less fragile and cannot be broken down, so they accumulate in the blood
Respuesta
  • True
  • False

Pregunta 12

Pregunta
Which of the following are symptoms of M.M.A?
Respuesta
  • Hypersegmented neutrophils
  • Giant Metamelanocytes

Pregunta 13

Pregunta
Which of the following are results of EXTREME B12/Folate deficiency?
Respuesta
  • Dementia
  • Neuropathy
  • Jaundice

Pregunta 14

Pregunta
What is the role of B12?
Respuesta
  • A Co-Enzyme
  • A substrate for globin production
  • A neurotransmitter

Pregunta 15

Pregunta
B12 is only synthesised in micro-organisms
Respuesta
  • True
  • False

Pregunta 16

Pregunta
Where is B12 stored?
Respuesta
  • The liver
  • The kidneys
  • The spleen

Pregunta 17

Pregunta
GI diseases, tapeworm and a lack of intrinsic factor all cause what?
Respuesta
  • Malapsorption of B12
  • Failure of B12 metabolism
  • Transcabalmin II deficiency

Pregunta 18

Pregunta
Transcabalmin II (TCII) deficiency can be tested for
Respuesta
  • True
  • False

Pregunta 19

Pregunta
Folate is very sensitive to cooking and will degrade easily
Respuesta
  • True
  • False

Pregunta 20

Pregunta
How long will the liver stores of folate last?
Respuesta
  • 3 weeks
  • 3 months
  • 3 years

Pregunta 21

Pregunta
Pregnancy and chronic haemolytic conditions cause what?
Respuesta
  • Inc Folate requirement
  • Inadequate folate intake
  • Folate malabsorption

Pregunta 22

Pregunta
Folate deficiency can be drug induced
Respuesta
  • True
  • False

Pregunta 23

Pregunta
Folate is vital for rapidly dividing cells
Respuesta
  • True
  • False

Pregunta 24

Pregunta
Folate deficiency can cause....
Respuesta
  • Spinal cord degeneration
  • Abnormal skin development
  • Everything starts tasting of fish
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