Fichas
Metoprolol pharmacokinetics
Fichas del conjunto (6)
- 1The steps in pharmacokineticsDADME
Dissolution
Absorption
Distribution
Metabolism
Excretion - 2DissolutionEasily dissolved in the stomach and GIT
- 3AbsorptionQuickly and readily absorbed by the GIT into circulation
- 4DistributionQuickly distributed across the body (3 - 6 hour half-life) Can cross the blood-brain barrier, and cross the placenta as well as enter breast milk.
- 5MetabolismHas a 50% oral bioavailability due to the first pass effect - readily metabolised by the liver - into three different metabolites
- 6ExcretionExtensively (95%) excreted by the kidneys as metabolites and a small amount of unmetabolised drug
Información
- Descripción
- El usuario ha eliminado su información de asignaturas Fichas sobre Metoprolol pharmacokinetics, creado por Usuario eliminado el 10/06/2018.
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- Creado por Em J · 10 jun 2018
- Copiado por Em J · 10 jun 2018
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