PE Unit 8 HRQL and Health Status Measures

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Unit 8 Objs.
Sam Adeyiga
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Sam Adeyiga
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Define HRQL is the part of a person’s overall QoL that “represents the functional effect of an illness and its consequent therapy upon a patient, as perceived by the patient
Define QoL 1. a broad concept with many aspects that measures people’s overall perception of their life. 2. includes both health-related and non–health-related aspects of their lives (e.g., economic, political, cultural)
Importance of HRQL 1. it helps in measuring the overall impact of diseases and their treatments. 2. It helps to measure other aspect of heath called domain, such as such as psychological and social functioning. 3. can be used to detect otherwise undiagnosed or undetected diseases such as depression.
Utility Measures (UM) or QALY Measures 1. Use SG and TTO to measure UM 2. estimate the utility or values that individuals assign to different health states. 3. Pt chooses btw SG and TTO (termed Preference-based or Choice-based measure) 4. Utility value is btw 0 - 1 and is multiplied by the length of time in each health state.
Disadvantage of Utility measures time consuming and resources-intensive
Use of non- QALY HRQL measures 1. AKA nonutility or nonpreference measures 2. measure the effect of trt and diseases from a pt's viewpoint 3. mostly multidimensional w/ many overall scores or scores for each aspects or domains of the pt's health
Disadvantages of non- QALY HRQL measures 1. Result is more difficult to use bc of multidimensional health status measures 2. The range of possible scores differ btw the variety of health status instruments (surveys) available, complicating interpretation issues.
Advantages of General or Generic Measures 1. Can be broadly applied 2. Scores can be compared for many disease states and conditions. 3. It summarizes range of concepts 4. May detect unanticipated effects
Disadvantages of General or Generic Measures 1. May not be sensitive (responsive) to clinically relevant differences for every disease or condition. 2. May not be responsive to changes in health. 3. May not be relevant for specific populations. 4. Results may be difficult to interpret
Examples of General or Generic Measures 1. Medical Outcome Study Short-Form Health Surveys (MOS-SF) which includes a. SF-12 b. SF-36, and c. SF-36 Version 2) 2. Quality of Well-Being (QWB) Scale 3. Sickness Impact Profile (SIP) 4. Dartmouth COOP
Disease-specific measures 1. often used to collect more narrowly focused patient views on the impact of the disease. 2. Examples of specific areas investigated with disease-specific questionnaires include sexual functioning for erectile dysfunction treatment, nausea and vomiting for cancer treatment, and range of movement for arthritis treatment
Validity
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