Tourette's Disorder

Tourette's Disorder

1. Neurodevelopmental disorder characterized by motor and vocal tics

   • physical discomfort
     • Difficulties concentrating
       • Relationship problems
         • Academic, cognitive and emotional difficulties

2. Comorbid with:

   • ODD
   • Anxiety
   • Depresion
   • ADHD
   • OCD

3. Caused by dysfunctional modulation of DA and GABA in CSTC

   • cortico-striatal-thalamo-cortical (CSTC) pathway
     • brain circuit that controls movement execution, habit formation and reward
     • Motor circuit
     • Oculomotor
     • Prefrontal
       • Planification, execution and inhibition of movement, motivational regulation of behavior, error detection and asociative learning
     • Orbitofrontal
     • Cingulado
   • This dificults motor learning

4. Treatment for Tourette

   • Treatment for Tourette 

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