Nucleic Acids

Descripción

Bachelors Degree Bionanophysics Mapa Mental sobre Nucleic Acids, creado por Chloe Foulkes el 01/03/2016.
Chloe Foulkes
Mapa Mental por Chloe Foulkes, actualizado hace más de 1 año
Chloe Foulkes
Creado por Chloe Foulkes hace alrededor de 8 años
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Resumen del Recurso

Nucleic Acids
  1. Electromagnetic Force
    1. Only relevant force for this scale
      1. All intermolecular forces
        1. Charge mediated
          1. Attractive and Repulsive
          2. F(r)=-(nCm1m2)/r^(n+1)
            1. Long range interactions disappear for n>3
              1. Lennard- Jones type potential graphs
                1. Positive energy = Repulsive force
                  1. Negative energy = Attractive Force
                    1. Lennard- Jones: V(r)= -A/r^6 + B/r^12
                  2. Polymers
                    1. Made up of monomers
                      1. Joined via covalent bonds
                      2. Degree of polymization = number of monomers = N
                        1. Mass of polymer= Nm(mon)
                          1. Types
                            1. Homopolymers
                              1. Same monomer
                              2. Heteropolymer
                                1. Different monomers
                                  1. Random
                                    1. Block
                                2. Flexibility
                                  1. Coil
                                    1. Rod
                                      1. Depends on length scale
                                      2. Isomerisation
                                        1. Isotatic
                                          1. Chemical group always in same position
                                          2. Syndiotactic
                                            1. Chemical group swaps sides
                                            2. Atactic
                                              1. Chemical group in random positon
                                            3. Topology
                                              1. Linear
                                                1. Ring
                                                  1. Branched
                                                2. Molecular Conformations
                                                  1. Free Jointed Chain (FJC) Model
                                                    1. Mean squared value= Cn*n*l^2
                                                      1. Cn=Flory Characteristic Ratio – average of all Ci, converging for C∞
                                                        1. l= bond length
                                                          1. n= number of bond lengths
                                                          2. No correlations between all θij, and all θij allowable
                                                            1. Equivalent FJC
                                                              1. N=L^2/(
                                                                1. L= Contour length
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