A Lot of Fuss

A Lot of Fuss

1. Celiac Disease

   • Signs & Symptoms
     • Adults
       • Anemia
       • Fatigue
       • Diarrhea
       • weight loss
       • bloating and gas
       • abdominal pain
       • nausea
       • constipation
       • vomiting
       • Damage to dental enamel
     • Children
       • Muscle wasting
       • vomiting
       • Swollen belly
       • Failure to thrive
       • Poor appetite
       • Irritability
       • constipation
   • Risk factors
     • Family history
     • Autoimmune disorder
     • Genetic disorders
     • Age & Gender
     • Ethnicity
     • Sjogren's syndrome
   • Causes
     • Intolerance to gluten
     • HLA-DQ2 & DQ8
       • Increases risk of disease, but not every person who has this gene will necessarily develop it
         • First-degree relatives have a 40% chance, so they have to do genetic testing
   • Pathogenesis & Immunology
   • Complications
     • Lactose intolerance
     • Malnutrition
     • Bone loss
       • Osteoporosis
         • Bone density test
     • Infertility
     • Cancer
     • Psychological
       • Anxiety
       • Depression
   • Investigations
     • Serology
     • IgA TTG
     • Physical examination
       • Protuberant and Tympanic abdomen
       • Weight loss
       • Orthostatic hypotension
       • Ascites
       • Cheilosis and glossitis
       • Dermatitis herpetiformis
       • Ecchymoses
       • Evidence of peripheral neuropathy
       • Chvostek sign
     • Stool exam
     • Hematologic tests
     • Electrolytes
     • Oral tolerance test
     • CT enteroclysis
     • Endoscopy & biopsy
   • Management
     • Gluten-free diet
     • psychological factors the promote lifestyle modification
       • family support
       • medical advice
       • talk to a friend
       • make a plan
       • reduce the stress

2. Mohammed 40 year old Complains of tiredness, stomach cramps ,bloating and Flatulence. Celiac disease was confirmed and he started gluten free diet

3. Anatomy of small intestines

   • embryology

4. Gas and bloating

   • Source of Gas
     • Air swallowing
     • Bacterial production
   • CAUSES OF INCREASED GAS
     • Swallowed air
     • Foods that cause gas
     • Lactose intolerance
     • Intolerance to food sugars
     • Diseases associated with increased gas

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