weight loss

weight loss

1. Decreased appetitie

   • Dysphagia
     • 1. Prehension 2. Mastication 3. Swallowing
   • Inflammatory diseases of the mouth
     • Local
       • 1. dental disease 2. FB's 3. irritants 4. eosinophilic complex (cats) 5. lymphocytic plasmacytic stomatitis 6. Neoplasms       benign: papillomas, epulis      malignant: melanoma, sq cell carcinoma, fibrosarcoma
     • Systemic
       • 1. uraemia 2. viral inf. cat (FIV, FeLV, FIP) 3. autoimmune (pemphigus) 4. neutropenia (drug dyscrasis-PBZ, and bone marrow failure)
   • general disease conditions
   • Pyshological
     • Diet and environment change

2. Normal or increased appetite

   • Q. Is it weight loss or muscle wasting (check CPK and AST levels).
   • Malassimulation
     • malabsorption
       • Normal TLI faeces split fats (free fatty acids)
       • Primary GI causes
         • Always need a biopsy for confirmation 1.  Plasmacytic / lymphacytic enteritis 2. Lymphangiectasia 3. GI lymphoma 4..Severe ARD 5. eosinophilic enteritis 6. dietary intolerance/hypersensitivity 7. granulomatous FIP
       • secondary GI causes
         • 1. Hyperthyroidism in CATS 2. Liver disease
     • Maldigestion = EPI
       • Other causes include  1. secondary enzyme deficiency 2. deficiency of bile acids (liver disease) 3. loss of brush border enzymes.
   • Malutilisation
     • 1. Diabetes mellitus 2. CHF 3  Neoplasia 4. Hyperparathyroidism 5. Liver disease 6. Renal disease 7. Hyperadrenocorticism