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Reproductive Systems - Female reproduction III

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  1. 1Endometrium development - Menstrual phaseFirst 4 days
    Endo. lining of uterus discarded
    Bleeding due to ruptured BV in endometrium
    Expelled as menstrual fluid
  2. 2Proliferation phaseOestrogen secreted by developing follicle leads to growth + thickening of the endometrium
    Uterine glands develop in endo, don't secrete yet
  3. 3Secretory (progestational) phaseC.L. secretes pro + oestradiol
    Prog + uterine glands to produce uterine milk - high in pro + glycogen
    Provides correct environment should ovum fertilisation occur
  4. 4New menstrual phaseC.L. regresses
    no prog/o
    endo no longer maintained, necrosis occurs
    Expelled w blood as menstrual fluid
  5. 5ImplantationFertilised ovum begins to divide, reaches uterus in 3/4 days
    gives time for endom to develop to a suitable state for imp. of developing blastocysts
  6. 6Day 9By day 9 the blast/developing placenta produce human chorionic gondaotrophin (HCG) at high levels for 8 weeks
  7. 7Function of hCGprevents C.L. from regressing
  8. 8Egg fertilisedhCG signals CL to continue prog. secretion
  9. 9False negativehCG drops at 4 months, gives off false negative
    Placenta then takes over hCG secretion.
  10. 10PlacentaEndocrine organ
    hCG
    Progesterone
    oESTROGEN
    hPL
  11. 11hCGensures continued secretion of progesterone in early pregnancy
  12. 12ProgesteroneMaintains endometrium
    decr. myometrial excitability
    Stimulates mammary development
  13. 13OestrogenImportant for build up of uterine muscle + mammary development
  14. 14hPLHuman placental lactogen
    Secreted ~ 10 weeks into gestation
    Regulates foetal growth and co-ordinates foetal/maternal metabolism
  15. 15PartuiritionContraction of myometrium sufficiently strong enough to expel foetus
  16. 16Contractions + by:High O:Prog ratio that occurs towads end of pregnancy
    Upregulates OXYTOCIN R in myometrium
    Circulating oxytocin can bind + induce muscle contraction
  17. 17(2)Pressure of foetus against cervix
  18. 18example of?Neuroendocrine reflex
  19. 19MOA^ Oxytocin secretion from P.P.
    Stronger contractions
    +FDBCK cycle progressively ^ until cervical dilation + delivery are completed.
  20. 20(3)PFF-2alpha stims uterine contraction
  21. 21Synthetic oxytocinPitocin
  22. 22LactationDuring gestation elevated placental O/Prog. promotes development of ducts + alveoli in mammary glands
  23. 23Prolactinstim. synthesis of enzymes essential for milk production by alveolar epithelial cells
  24. 24What stim lactation?Withdrawal of placental steroids
    (removal of placenta)
  25. 25SucklingSustains lactation
    Triggers release of oxy/prolactin
    ox = milk ejection
    pro = milk synth.
  26. 26Hormone feedback sucklingsuckling
    Mechanoreceptors in nipple
    Hypothalamus
    Nervous pathway / dopamine
    P.P. / A.P.
    ^ Oxytocin / ^ prolactin
    contraction / milk synth

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El usuario ha eliminado su información de asignaturas Fichas sobre Reproductive Systems - Female reproduction III, creado por Usuario eliminado el 05/04/2018.
Creado por
Usuario eliminado · abr 2018
Actualizado
5 abr 2018
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13
Historial
  • Creado por J yadonknow · 5 abr 2018
  • Copiado por J yadonknow · 5 abr 2018
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